Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 6/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 6/20 | 0.33 |
| ▸ | WNT1 | P04628 | 5/20 | 0.33 |
| ▸ | ALK | Q9UM73 | 3/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.32 |
| ▸ | GSK3B | P49841 | 3/20 | 0.31 |
| ▸ | WNT3A | P56704 | 1/20 | 0.31 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.31 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | CBLB | Q13191 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5232310 | 0.84 | ABL1 (0.36) | ABL1DYRK1AWNT1ALKTRPV1 | |
| SCHEMBL5235907 | 0.81 | ABL1 (0.35) | ABL1DYRK1AWNT1TRPV1GSK3B | |
| SCHEMBL5235799 | 0.81 | MAPT (0.47) | ABL1 | |
| SCHEMBL5239092 | 0.79 | MEN1 (0.41) | — | |
| SCHEMBL5236739 | 0.79 | HTR1A (0.44) | — | |
| SCHEMBL5236415 | 0.78 | ADAMTS5 (0.40) | — | |
| SCHEMBL5236348 | 0.77 | CHRNB2 (0.40) | IDO1 | |
| SCHEMBL5235440 | 0.76 | ALDH1A1 (0.40) | — | |
| SCHEMBL5239779 | 0.76 | MAPT (0.40) | — | |
| SCHEMBL5231416 | 0.76 | NOTUM (0.49) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1701946-B1 | DERIVATIVES OF 1-PIPERAZINE- AND 1-HOMOPIPERAZINE-CARBOXYLATES, PREPARATION METHOD THEREOF AND USE OF SAME AS INHIBITORS OF THE FAAH ENZYME | SANOFI AVENTIS (FR) | 2007-12-19 | — | — | EP | claimed |