Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.48 |
| ▸ | FGFR2 | P21802 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | TYR | P14679 | 1/20 | 0.47 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.45 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5233312 | 0.81 | FGFR1 (0.47) | L3MBTL1MAPTHSD17B10NPSR1FGFR1 | |
| SCHEMBL5237364 | 0.78 | TP53 (0.49) | L3MBTL1MAPTKMT2AMEN1SLC6A7 | |
| SCHEMBL5239479 | 0.77 | FGFR1 (0.41) | L3MBTL1MAPTHSD17B10NPSR1FGFR1 | |
| SCHEMBL5239166 | 0.77 | ALDH1A1 (0.56) | L3MBTL1MAPTHSD17B10NPSR1KMT2A | |
| SCHEMBL5240923 | 0.76 | RBP4 (0.56) | MAPTNPSR1TGFBR1ACVR1ALOX15 | |
| SCHEMBL5237158 | 0.75 | KMT2A (0.68) | MAPTHSD17B10KMT2AMEN1SLC6A7 | |
| SCHEMBL5239486 | 0.74 | FGFR1 (0.41) | L3MBTL1MAPTHSD17B10NPSR1FGFR1 | |
| SCHEMBL632109 | 0.73 | CA12 (0.69) | HSD17B10NPSR1KMT2AMEN1SLC6A7 | |
| SCHEMBL5234854 | 0.73 | RAB9A (0.54) | L3MBTL1MAPTKMT2AMEN1TP53 | |
| SCHEMBL5234829 | 0.73 | GRM5 (0.54) | MAPTHSD17B10NPSR1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1701946-B1 | DERIVATIVES OF 1-PIPERAZINE- AND 1-HOMOPIPERAZINE-CARBOXYLATES, PREPARATION METHOD THEREOF AND USE OF SAME AS INHIBITORS OF THE FAAH ENZYME | SANOFI AVENTIS (FR) | 2007-12-19 | — | — | EP | claimed |