Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 4/20 | 0.41 |
| ▸ | FGFR2 | P21802 | 4/20 | 0.41 |
| ▸ | ERN1 | O75460 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 3/20 | 0.35 |
| ▸ | DRD4 | P21917 | 3/20 | 0.35 |
| ▸ | DRD3 | P35462 | 3/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.34 |
| ▸ | USP2 | O75604 | 4/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5234847 | 0.84 | KMT2A (0.40) | HSD17B10MAPTALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL5236705 | 0.84 | CD274 (0.41) | ERN1MAPTNPSR1ALDH1A1CYP3A4 | |
| SCHEMBL5232294 | 0.83 | ALDH1A1 (0.39) | HSD17B10MAPTALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL5236214 | 0.82 | RXRA (0.39) | ERN1MAPTNPSR1ALDH1A1SMN1; SMN2 | |
| SCHEMBL5239479 | 0.82 | FGFR1 (0.41) | FGFR1FGFR2ERN1DRD2DRD4 | |
| SCHEMBL5236555 | 0.82 | USP2 (0.41) | DRD3HSD17B10MAPTALDH1A1CYP3A4 | |
| SCHEMBL5240799 | 0.81 | NAAA (0.40) | FGFR1DRD4HSD17B10MAPTALDH1A1 | |
| SCHEMBL5233074 | 0.81 | L3MBTL1 (0.44) | MAPTALDH1A1MAPK1L3MBTL1MEN1 | |
| SCHEMBL5238192 | 0.80 | CYP2C19 (0.37) | HSD17B10MAPTNPSR1ALDH1A1CYP3A4 | |
| SCHEMBL5234068 | 0.79 | DRD2 (0.45) | DRD2DRD4DRD3ALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1701946-B1 | DERIVATIVES OF 1-PIPERAZINE- AND 1-HOMOPIPERAZINE-CARBOXYLATES, PREPARATION METHOD THEREOF AND USE OF SAME AS INHIBITORS OF THE FAAH ENZYME | SANOFI AVENTIS (FR) | 2007-12-19 | — | — | EP | claimed |