Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | HTR1A | P08908 | 2/20 | 0.48 |
| ▸ | HTR1D | P28221 | 2/20 | 0.48 |
| ▸ | HTR1B | P28222 | 2/20 | 0.48 |
| ▸ | HTR2A | P28223 | 2/20 | 0.48 |
| ▸ | HTR2C | P28335 | 1/20 | 0.48 |
| ▸ | HTR6 | P50406 | 1/20 | 0.48 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.47 |
| ▸ | LCK | P06239 | 1/20 | 0.47 |
| ▸ | MAP4K3 | Q8IVH8 | 1/20 | 0.47 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5238577 | 0.81 | GRM5 (0.50) | TP53HTR6MEN1KMT2AMAPT | |
| SCHEMBL5239584 | 0.80 | CD274 (0.45) | TP53HTR1AHTR1DHTR1BHTR2A | |
| SCHEMBL1581921 | 0.79 | KDM4E (0.50) | CD274MAPTLMNAHTTSMN1; SMN2 | |
| SCHEMBL8320029 | 0.79 | ALK (0.55) | MAPTGAALMNAL3MBTL1GFER | |
| SCHEMBL5239166 | 0.79 | ALDH1A1 (0.56) | HTR1AHTR1DHTR1BMEN1KMT2A | |
| SCHEMBL5234854 | 0.78 | RAB9A (0.54) | TP53MEN1KMT2AMAPTGAA | |
| SCHEMBL5240923 | 0.78 | RBP4 (0.56) | HTR1AHTR1DHTR1BHTR2AHTR2C | |
| SCHEMBL5237133 | 0.78 | L3MBTL1 (0.49) | TP53MEN1KMT2AMAPTL3MBTL1 | |
| SCHEMBL5237158 | 0.77 | KMT2A (0.68) | TP53MEN1KMT2AMAPTGAA | |
| SCHEMBL3774486 | 0.76 | ALDH1A1 (0.46) | MEN1KMT2AMAPTGAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1701946-B1 | DERIVATIVES OF 1-PIPERAZINE- AND 1-HOMOPIPERAZINE-CARBOXYLATES, PREPARATION METHOD THEREOF AND USE OF SAME AS INHIBITORS OF THE FAAH ENZYME | SANOFI AVENTIS (FR) | 2007-12-19 | — | — | EP | claimed |