Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 1/20 | 0.34 |
| ▸ | AOC3 | Q16853 | 10/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.32 |
| ▸ | SCD | O00767 | 1/20 | 0.30 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5237172 | 0.87 | AOC3 (0.37) | AOC3 | |
| SCHEMBL5236354 | 0.84 | CHRNB2 (0.38) | — | |
| SCHEMBL5237139 | 0.81 | RORC (0.37) | RORCAOC3HRH3 | |
| SCHEMBL5237467 | 0.81 | PANK3 (0.40) | RORCAOC3HRH3 | |
| SCHEMBL5238192 | 0.79 | CYP2C19 (0.37) | — | |
| SCHEMBL5232377 | 0.78 | SMN1; SMN2 (0.37) | — | |
| SCHEMBL5236555 | 0.77 | USP2 (0.41) | FFAR4 | |
| SCHEMBL5233074 | 0.77 | L3MBTL1 (0.44) | — | |
| SCHEMBL5237329 | 0.76 | CA2 (0.40) | — | |
| SCHEMBL5235907 | 0.76 | ABL1 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1701946-B1 | DERIVATIVES OF 1-PIPERAZINE- AND 1-HOMOPIPERAZINE-CARBOXYLATES, PREPARATION METHOD THEREOF AND USE OF SAME AS INHIBITORS OF THE FAAH ENZYME | SANOFI AVENTIS (FR) | 2007-12-19 | — | — | EP | claimed |