Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 17/20 | 0.37 |
| ▸ | PARP1 | P09874 | 2/20 | 0.30 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
| ▸ | PARP6 | Q2NL67 | 1/20 | 0.30 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5237148 | 0.87 | RORC (0.34) | AOC3 | |
| SCHEMBL5236354 | 0.85 | CHRNB2 (0.38) | — | |
| SCHEMBL5237166 | 0.81 | AOC3 (0.41) | AOC3PARP1PARP2KCNH2 | |
| SCHEMBL5238192 | 0.80 | CYP2C19 (0.37) | — | |
| SCHEMBL5232294 | 0.79 | ALDH1A1 (0.39) | — | |
| SCHEMBL5230481 | 0.79 | ITGB3 (0.39) | — | |
| SCHEMBL5236555 | 0.78 | USP2 (0.41) | — | |
| SCHEMBL5233074 | 0.77 | L3MBTL1 (0.44) | — | |
| SCHEMBL5237176 | 0.77 | NPC1 (0.35) | — | |
| SCHEMBL5235809 | 0.76 | MAPT (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1701946-B1 | DERIVATIVES OF 1-PIPERAZINE- AND 1-HOMOPIPERAZINE-CARBOXYLATES, PREPARATION METHOD THEREOF AND USE OF SAME AS INHIBITORS OF THE FAAH ENZYME | SANOFI AVENTIS (FR) | 2007-12-19 | — | — | EP | claimed |