SCHEMBL524506

SCHEMBL524506

CCc1cc(NC(O)(O)CC)ccc1C(=O)O

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CLCN2 P51788 2/20 0.38
▸ ALDH1A1 P00352 4/20 0.38
▸ MEN1 O00255 3/20 0.38
▸ KMT2A Q03164 3/20 0.38
▸ USP2 O75604 2/20 0.38
▸ HPGD P15428 1/20 0.38
▸ TSHR P16473 1/20 0.38
▸ GABRP O00591 2/20 0.37
▸ GABRD O14764 2/20 0.37
▸ GABRA1 P14867 2/20 0.37
▸ GABRB1 P18505 2/20 0.37
▸ GABRG2 P18507 2/20 0.37
▸ GABRB3 P28472 2/20 0.37
▸ GABRA5 P31644 2/20 0.37
▸ GABRA3 P34903 2/20 0.37
▸ GABRA2 P47869 2/20 0.37
▸ GABRB2 P47870 2/20 0.37
▸ GABRA4 P48169 2/20 0.37
▸ GABRE P78334 2/20 0.37
▸ GABRA6 Q16445 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL128615 0.80 GRIN2C (0.35) CLCN2ALDH1A1MEN1KMT2AUSP2
SCHEMBL8856987 0.78 GABRP (0.42) CLCN2ALDH1A1MEN1KMT2AUSP2
SCHEMBL1839262 0.77 MAPT (0.54) CLCN2ALDH1A1MEN1KMT2AUSP2
SCHEMBL11523096 0.77 ALDH1A1 (0.42) CLCN2ALDH1A1MEN1KMT2AUSP2
SCHEMBL2922856 0.76 ALDH1A1 (0.39) CLCN2ALDH1A1MEN1KMT2AUSP2
Hydrochloric Acid SCHEMBL8785708 0.76 MAPT (0.53) CLCN2ALDH1A1MEN1KMT2AUSP2
SCHEMBL8888227 0.76 POLB (0.55) MEN1KMT2AHPGDMAPTKDM4E
SCHEMBL9141154 0.74 MAPT (0.51) CLCN2ALDH1A1MEN1KMT2AHPGD
SCHEMBL5321364 0.73 ABCC9 (0.57) MEN1KMT2ATSHR
SCHEMBL3385017 0.72 ALDH1A1 (0.52) ALDH1A1MEN1KMT2AUSP2HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 72 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9314488-B2 Cellular extracts REGENICS AS (NO) 2016-04-19 — — US claimed
US-8877253-B2 Cellular extracts REGENICS AS (NO) 2014-11-04 — — US claimed
US-20120121673-A1 Topical Compositions Comprising Inorganic Particulates And An Alkoxylated Diphenylacrylate Compound SUSAK MILANKA (CA) 2012-05-17 — — US claimed
US-12458687-B2 Wound debridement systems REGENICS AS (NO) 2025-11-04 — — US disclosed
EP-3866818-B1 USE OF FISH EGG CELLULAR EXTRACTT FOR WOUND HEALING REGENICS AS (NO) 2025-07-23 — — EP disclosed
US-20220370503-A1 METHODS AND DEVICES FOR THE PRODUCTION AND DELIVERY OF BENEFICIAL FACTORS FROM STEM CELLS AELAN CELL TECHNOLOGIES, INC. 2022-11-24 — — US disclosed
US-20220347273-A1 WOUND DEBRIDEMENT SYSTEMS REGENICS AS (NO) 2022-11-03 — — US disclosed
US-20220288095-A1 SIALIC ACID FOR USE IN THE TREATMENT OF PSORIASIS LIFESCIENCE AS (NO) 2022-09-15 — — US disclosed
EP-4003365-A1 SIALIC ACID FOR USE IN THE TREATMENT OF PSORIASIS Lifescience AS (NO) 2022-06-01 — — EP disclosed
EP-3993765-A1 WOUND DEBRIDEMENT SYSTEMS Regenics AS (NO) 2022-05-11 — — EP disclosed
CN-114450026-A Sialic acid for use in the treatment of psoriasis 生命科学股份有限公司 2022-05-06 — — CN disclosed
US-20030176345-A1 Wound healing composition and method for use thereof DAWSON MONICA E (US) 2003-09-18 — — US disclosed
US-6541447-B1 Mixture of ovalbumin, phenoxyethanol, carbomer and triethanolamine B & M HEALTHCARE TECHNOLOGIES, INC. 2003-04-01 — — US disclosed
US-6514744-B2 Skin moisturizer KIBUN FOOD CHEMIFA CO., LTD. (JP) 2003-02-04 — — US disclosed
US-20020164351-A1 External compositions for skin comprising sphingoglycolipid KIBUN FOOD CHEMIFA CO., LTD. (JP) 2002-11-07 — — US disclosed
US-6348201-B2 SPHINGOGLYCOLIPID AVAILABLE AS COSMETIC AND MEDICINE, HAS POTENT MOISTURIZING EFFEACT AND PREVENTIVE EFFECT AGAINST SKIN ROUGHNESS; SPHINOGGLYCOLIPID CONTAINING SUGAR MOITIES AND AMIDE GROUP KIBUN FOOD CHEMIFA CO., LTD. (JP) 2002-02-19 — — US disclosed
US-20020006414-A1 EXTERNAL COMPOSITION FOR SKIN COMPRISING SPHINGOGLYCOLIPID FOODCHEMIFA CO., LTD. (JP) 2002-01-17 — — US disclosed
EP-0887070-A1 External composition for skin comprising sphingoglycolipid Kibun Food ChemiFA Co., Ltd. (JP) 1998-12-30 — — EP disclosed
US-5766575-A APPLYING A PHENOLIC DERIVATIVE CHESEBROUGH-POND'S USA CO., DIVISION OF CONOPCO, INC. (US) 1998-06-16 — — US disclosed
US-5460832-A Skin cosmetic having an egg white enzyme hydrolysate with hyaluronic acid synthesis promoting activity TAIYO KAGAKU CO., LTD. (JP) 1995-10-24 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020164351-A1 External compositions for skin comprising sphingoglycolipid UGCG, UGGT1, MAN1B1 CLCN2 1718/4885ALDH1A1 785/4885MEN1 3414/4885
US-20120121673-A1 Topical Compositions Comprising Inorganic Particulates And An Alkoxylated Diphenylacrylate Compound CUTA, ALAD, AAAS CLCN2 2659/4885ALDH1A1 53/4885MEN1 3933/4885
US-20020006414-A1 EXTERNAL COMPOSITION FOR SKIN COMPRISING SPHINGOGLYCOLIPID UGCG, MAN2A1, GALK1 CLCN2 2267/4885ALDH1A1 444/4885MEN1 3916/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback