Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 known ✓ | O43570 | 6/20 | 0.38 |
| ▸ | CA1 known ✓ | P00915 | 6/20 | 0.38 |
| ▸ | CA2 known ✓ | P00918 | 6/20 | 0.38 |
| ▸ | CA4 known ✓ | P22748 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 4/20 | 0.39 |
| ▸ | CA9 | Q16790 | 6/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | FAHD1 | Q6P587 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL38660376 | 1.00 | EPHX1 (0.39) | EPHX1CA12CA1CA2CA9 | |
| SCHEMBL5244938 | 1.00 | EPHX1 (0.39) | EPHX1CA12CA1CA2CA9 | |
| Potassium Ion SCHEMBL29116637 | 0.97 | CA4 (0.39) | EPHX1CA12CA1CA2CA9 | |
| Potassium Ion SCHEMBL6894484 | 0.94 | EPHX1 (0.39) | EPHX1CA12CA1CA2CA9 | |
| Zinc Ion SCHEMBL2411292 | 0.94 | EPHX1 (0.39) | EPHX1CA12CA1CA2CA9 | |
| SCHEMBL504432 | 0.94 | EPHX1 (0.39) | EPHX1CA12CA1CA2CA9 | |
| Lithium Ion SCHEMBL1588970 | 0.94 | EPHX1 (0.39) | EPHX1CA12CA1CA2CA9 | |
| SCHEMBL21808834 | 0.94 | EPHX1 (0.39) | EPHX1CA12CA1CA2CA9 | |
| SCHEMBL21808833 | 0.94 | EPHX1 (0.39) | EPHX1CA12CA1CA2CA9 | |
| SCHEMBL1893677 | 0.94 | EPHX1 (0.39) | EPHX1CA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 93 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118978794-A | Preparation method of chain-extended nucleation modified poly (butylene succinate) | 华东理工大学 | 2024-11-19 | — | — | CN | claimed |
| CN-115785523-B | Composition and application of alpha/beta composite nucleating agent for regulating and controlling mechanical properties of polypropylene | 华东理工大学 | 2023-10-10 | — | — | CN | claimed |
| CN-115785523-A | Composition and application of alpha/beta composite nucleating agent for regulating and controlling mechanical property of polypropylene | 华东理工大学 | 2023-03-14 | — | — | CN | claimed |
| CN-113896946-A | Special composite additive for polypropylene geogrid and special material for polypropylene geogrid comprising same | 呈和科技股份有限公司 | 2022-01-07 | — | — | CN | claimed |
| EP-2951239-B1 | INJECTION MOULDED POLYPROPYLENE ARTICLES | INEOS EUROPE AG (CH) | 2019-03-13 | — | — | EP | claimed |
| US-9969859-B2 | HDPE-based buffer tubes with improved excess fiber length in fiber optic cables | DOW GLOBAL TECHNOLOGY LLC (US) | 2018-05-15 | — | — | US | claimed |
| EP-2935454-B1 | HDPE-BASED BUFFER TUBES WITH IMPROVED EXCESS FIBER LENGTH IN FIBER OPTIC CABLES | DOW GLOBAL TECHNOLOGIES LLC (US) | 2018-02-21 | — | — | EP | claimed |
| US-9738761-B2 | Injection moulded polypropylene articles | INEOS EUROPE AG (CH) | 2017-08-22 | — | — | US | claimed |
| EP-2951239-A1 | INJECTION MOULDED POLYPROPYLENE ARTICLES | Ineos Europe AG (CH) | 2015-12-09 | — | — | EP | claimed |
| US-20150322215-A1 | INJECTION MOULDED POLYPROPYLENE ARTICLES | BARCLAYS BANK PLC (GB) | 2015-11-12 | — | — | US | claimed |
| US-20150315355-A1 | HDPE-Based Buffer Tubes with Improved Excess Fiber Length in Fiber Optic Cables | DOW GLOBAL TECHNOLOGIES LLC | 2015-11-05 | — | — | US | claimed |
| EP-2935454-A1 | HDPE-BASED BUFFER TUBES WITH IMPROVED EXCESS FIBER LENGTH IN FIBER OPTIC CABLES | Dow Global Technologies LLC (US) | 2015-10-28 | — | — | EP | claimed |
| WO-2014118149-A1 | INJECTION MOULDED POLYPROPYLENE ARTICLES | INEOS EUROPE AG (CH) | 2014-08-07 | — | — | WO | claimed |
| WO-2014099350-A1 | HDPE-BASED BUFFER TUBES WITH IMPROVED EXCESS FIBER LENGTH IN FIBER OPTIC CABLES | DOW GLOBAL TECHNOLOGIES LLC (US) | 2014-06-26 | — | — | WO | claimed |
| US-6562890-B2 | In combination with acid scavengers (such as organic calcium salts or dihydrotalcite complexes) that provide highly desirable and effective nucleating properties within polymer articles (such as polyolefins) are provided. | MILLIKEN & COMPANY | 2003-05-13 | — | — | US | claimed |
| US-6110251-A | WITH POLYMER, NUCLEATING AGENT AND ELECTROSTATIC CHARGING ENHANCER | JOHNS MANVILLE INTERNATIONAL, INC. (US) | 2000-08-29 | — | — | US | claimed |
| EP-4594398-A1 | FILM COMPRISING ETHYLENE COPOLYMERS OR TERPOLYMERS, METHOD FOR MAKING IT AND ITS USE AS SOLAR CELL ENCAPSULANT | Braskem S.A. (BR) | 2025-08-06 | — | — | EP | disclosed |
| CN-118978794-A | Preparation method of chain-extended nucleation modified poly (butylene succinate) | 华东理工大学 | 2024-11-19 | — | — | CN | disclosed |
| US-4197254-A | POSTEMERGENCE HERBICIDES | MONSANTO COMPANY (US) | 1980-04-08 | — | — | US | disclosed |
| US-3998863-A | ANTIOXIDANTS | AMERICAN CYANAMID COMPANY (US) | 1976-12-21 | — | — | US | disclosed |