Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.33 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | MLYCD | O95822 | 1/20 | 0.33 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | CASR | P41180 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3930203 | 0.80 | HTR2C (0.42) | HTR2CALDH1A1LMNATP53SMN1; SMN2 | |
| SCHEMBL3933844 | 0.79 | CTSK (0.44) | ALDH1A1MAPT | |
| SCHEMBL184424 | 0.79 | ANPEP (0.51) | SLC7A5ALDH1A1LMNASMN1; SMN2PTGS1 | |
| SCHEMBL305032 | 0.76 | L3MBTL1 (0.45) | SLC7A5ALDH1A1LMNASMN1; SMN2AAK1 | |
| SCHEMBL594359 | 0.76 | L3MBTL1 (0.45) | SLC7A5ALDH1A1LMNASMN1; SMN2AAK1 | |
| SCHEMBL30065221 | 0.76 | L3MBTL1 (0.45) | SLC7A5ALDH1A1LMNASMN1; SMN2AAK1 | |
| SCHEMBL8909021 | 0.76 | ADRB1 (0.46) | SLC7A5LMNA | |
| SCHEMBL7210714 | 0.76 | CPN1 (0.42) | SLC7A5ALDH1A1LMNAKMT2A | |
| SCHEMBL3922657 | 0.75 | MEN1 (0.45) | HTR2CALDH1A1LMNATP53SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL304679 | 0.75 | ATM (0.44) | SLC7A5ALDH1A1LMNASMN1; SMN2ITGA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1794135-A1 | SUBSTITUTED HETEROCYCLIC COMPOUNDS AND METHODS OF USE | Amgen Inc. (US) | 2007-06-13 | — | — | EP | disclosed |
| WO-2006037117-A1 | SUBSTITUTED HETEROCYCLIC COMPOUNDS AND METHODS OF USE | AMGEN INC. (US) | 2006-04-06 | — | — | WO | disclosed |