SCHEMBL527588

SCHEMBL527588

CS(=O)(=O)OCCC(CCOS(C)(=O)=O)CCOS(C)(=O)=O

nearest known ligand 0.57

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
USP2 O75604 2/20 0.57
TSHR P16473 2/20 0.57
ALDH1A1 P00352 2/20 0.57
KDM4E B2RXH2 1/20 0.57
LMNA P02545 1/20 0.57
MMP9 P14780 1/20 0.57
ALOX15 P16050 1/20 0.57
CA12 O43570 1/20 0.33
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
CA7 P43166 1/20 0.33
CA14 Q9ULX7 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4338211 0.87 USP2 (0.50) USP2TSHRALDH1A1KDM4ELMNA
SCHEMBL13030026 0.83 LMNA (0.46) USP2TSHRALDH1A1KDM4ELMNA
SCHEMBL3706344 0.81 ALDH1A1 (0.55) USP2TSHRALDH1A1KDM4ELMNA
SCHEMBL7618433 0.81 USP2 (0.55) USP2TSHRALDH1A1KDM4ELMNA
SCHEMBL10803892 0.80 CA1 (0.57) USP2TSHRALDH1A1KDM4ELMNA
SCHEMBL1762507 0.80 KDM4E (0.43) USP2TSHRALDH1A1KDM4ELMNA
SCHEMBL23149218 0.79 USP2 (0.52) USP2TSHRALDH1A1KDM4ELMNA
SCHEMBL30469514 0.79 USP2 (0.52) USP2TSHRALDH1A1KDM4ELMNA
Ethane Dimethane Sulfonate SCHEMBL1336145 0.78 USP2 (0.75) USP2TSHRALDH1A1KDM4ELMNA
SCHEMBL26211977 0.78 GSTK1 (0.47) USP2TSHRALDH1A1KDM4ELMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025233638-A1 RADIOPHARMACEUTICAL IMAGING METHOD OF ADENOMYOSIS SERAC HEALTHCARE LTD (GB) 2025-11-13 WO disclosed
US-20250186633-A1 METHODS FOR IMAGING INTEGRIN EXPRESSION AND FOR IMAGING SITES OF ENDOMETRIOSIS SERAC HEALTHCARE LTD (GB) 2025-06-12 US disclosed
CN-118785926-A Imaging integrin expression and intrauterine method for imaging a site of endometriosis 赛瑞科医疗有限公司 2024-10-15 CN disclosed
US-11723991-B2 Radiopharmaceutical compositions SERAC HEALTHCARE LIMITED (GB) 2023-08-15 US disclosed
US-20210060189-A1 RADIOPHARMACEUTICAL COMPOSITIONS SERAC HEALTHCARE LIMITED (GB) 2021-03-04 US disclosed
US-10758635-B2 Radiopharmaceutical compositions SERAC HEALTHCARE LIMITED (GB) 2020-09-01 US disclosed
EP-2598175-B1 RADIOPHARMACEUTICAL COMPOSITIONS SERAC HEALTHCARE LTD (GB) 2020-05-20 EP disclosed
EP-2680888-B1 TECHNETIUM LABELLED PEPTIDES GE HEALTHCARE LTD (GB) 2017-10-18 EP disclosed
US-9259496-B2 Technetium labelled peptides GE HEALTHCARE LIMITED (GB) 2016-02-16 US disclosed
US-8852550-B2 Chelator conjugates GE HEALTHCARE LIMITED (GB) 2014-10-07 US disclosed
US-20060120956-A1 Imaging agents comprising barbituric acid derivatives KOPKA KLAUS 2006-06-08 US disclosed
WO-2006032911-A2 METALLOPROTEINASE INHIBITOR IMAGING AGENTS GE HEALTHCARE LIMITED (GB) 2006-03-30 WO disclosed
EP-1404377-B1 IMPROVED CHELATOR CONJUGATES GE HEALTHCARE LTD (GB) 2005-09-21 EP disclosed
EP-1549317-A1 IMPROVED IMAGING AGENTS COMPRISING BARBITURIC ACID DERIVATIVES GE Healthcare Limited (GB) 2005-07-06 EP disclosed
WO-2005053752-A2 NOVEL IMAGING AGENTS COMPRISING CASPASE-3 INHIBITORS GE HEALTHCARE LIMITED (GB) 2005-06-16 WO disclosed
WO-2005049005-A1 INHIBITOR IMAGING AGENTS GE HEALTHCARE LIMITED (GB) 2005-06-02 WO disclosed
US-20040258619-A1 Diaminedioxime radiometal complexes GE HEALTHCARE LIMITED (GB) 2004-12-23 US disclosed
WO-2004032936-A1 IMPROVED IMAGING AGENTS COMPRISING BARBITURIC ACID DERIVATIVES AMERSHAM PLC (GB) 2004-04-22 WO disclosed
EP-1404377-A2 IMPROVED CHELATOR CONJUGATES GE Healthcare Limited (GB) 2004-04-07 EP disclosed
WO-2003006070-A2 IMPROVED CHELATOR CONJUGATES AMERSHAM PLC (GB) 2003-01-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040258619-A1 Diaminedioxime radiometal complexes DDO, DDT, DAO USP2 1003/4885TSHR 507/4885ALDH1A1 2084/4885
US-20060120956-A1 Imaging agents comprising barbituric acid derivatives CA5A, GABRA5, CA5B USP2 3515/4885TSHR 2922/4885ALDH1A1 1222/4885
US-11723991-B2 Radiopharmaceutical compositions TYMP, KIT, CHEK1 USP2 1110/4885TSHR 1973/4885ALDH1A1 3697/4885
US-20250186633-A1 METHODS FOR IMAGING INTEGRIN EXPRESSION AND FOR IMAGING SITES OF ENDOMETRIOSIS ITGB3, ITGB5, ITGAV USP2 3227/4885TSHR 1352/4885ALDH1A1 2726/4885
US-20210060189-A1 RADIOPHARMACEUTICAL COMPOSITIONS TYMP, KIT, CHEK1 USP2 1110/4885TSHR 1973/4885ALDH1A1 3697/4885
US-10758635-B2 Radiopharmaceutical compositions TYMP, KIT, CHEK1 USP2 1210/4885TSHR 2061/4885ALDH1A1 3674/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.