SCHEMBL5288600

SCHEMBL5288600

COc1ccccc1-c1ccc(Cl)cc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC6A4 P31645 1/20 0.51
SLC6A3 Q01959 1/20 0.51
PTPRC P08575 1/20 0.51
PTPN1 P18031 1/20 0.51
XDH P47989 1/20 0.51
GCGR P47871 1/20 0.51
MAPK14 Q16539 1/20 0.51
HTR7 P34969 1/20 0.50
KMT2A Q03164 1/20 0.50
FFAR2 O15552 2/20 0.49
APP P05067 1/20 0.48
CA12 O43570 1/20 0.48
CA1 P00915 1/20 0.48
CA2 P00918 1/20 0.48
CA4 P22748 1/20 0.48
CA7 P43166 1/20 0.48
CA9 Q16790 1/20 0.48
CA14 Q9ULX7 1/20 0.48
PTGS2 P35354 1/20 0.47
NR3C1 P04150 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31490154 1.00 SLC6A4 (0.51) SLC6A4SLC6A3PTPRCPTPN1XDH
Ammonia Solution, Strong SCHEMBL7626644 0.98 XDH (0.50) SLC6A4SLC6A3PTPRCPTPN1XDH
SCHEMBL24106783 0.83 ALDH1A1 (0.55) PTPRCPTPN1XDHHTR7APP
SCHEMBL8673950 0.83 CYP1A2 (0.48) SLC6A4SLC6A3XDHGCGRMAPK14
SCHEMBL294721 0.82 ALDH1A1 (0.58) PTPRCPTPN1XDHHTR7APP
SCHEMBL30136447 0.82 ALDH1A1 (0.58) PTPRCPTPN1XDHHTR7APP
SCHEMBL5690752 0.81 SQOR (0.55) SLC6A4SLC6A3PTPRCPTPN1XDH
SCHEMBL4425113 0.81 SYK (0.56) PTPRCPTPN1XDHHTR7APP
SCHEMBL1704521 0.81 ABL1 (0.62) PTPRCPTPN1XDHHTR7APP
SCHEMBL28311855 0.81 KDM4E (0.53) GCGRMAPK14KMT2AALDH1A1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104737271-B The manufacture method of Photocurable composition and film 佳能株式会社 2018-04-10 CN disclosed
CN-103885290-B Photosensitive polymer combination, the photosensitive element using it, the manufacture method of the forming method of Resist patterns and printed circuit board (PCB) 日立化成株式会社 2017-11-03 CN disclosed
CN-107251193-A Nanoimprint liquid material, method for producing pattern of cured product, method for producing optical component, and method for producing circuit board 佳能株式会社 2017-10-13 CN disclosed
CN-103885292-B Photosensitive polymer combination, the photosensitive element using it, the manufacture method of the forming method of Resist patterns and printed circuit board (PCB) 日立化成株式会社 2017-09-22 CN disclosed
CN-106990673-A A kind of transparent, photosensitive polyimide resin composition 浙江福斯特新材料研究院有限公司 2017-07-28 CN disclosed
CN-106796375-A Column formation resin combination, the manufacture method of substrate with column formation and the substrate with column formation 大日本印刷株式会社 2017-05-31 CN disclosed
US-20160155952-A1 COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2016-06-02 US disclosed
US-20160155952-A1 COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2016-06-02 US disclosed
EP-1313560-B1 CATALYST FOR AROMATIC C-O, C-N, and C-C BOND FORMATION UNIV YALE (US) 2007-12-19 EP disclosed
EP-1313560-B1 CATALYST FOR AROMATIC C-O, C-N, and C-C BOND FORMATION UNIV YALE (US) 2007-12-19 EP disclosed
US-20050256167-A1 Preparation and use of imidazole derivatives for treatment of obesity BAYER PHARMACEUTICALS CORPORATION (US) 2005-11-17 US disclosed
EP-1313560-A4 CATALYST FOR AROMATIC C-O, C-N, and C-C BOND FORMATION UNIV YALE (US) 2005-02-09 EP disclosed
EP-1313560-A1 CATALYST FOR AROMATIC C-O, C-N, and C-C BOND FORMATION YALE UNIVERSITY (US) 2003-05-28 EP disclosed
US-6562989-B2 Bicyclopentyl iron ligand and transition metal catalyst YALE UNIVERSITY 2003-05-13 US disclosed
US-20030008768-A1 Catalyst for aromatic C-O, C-N, and C-C bond formation NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2003-01-09 US disclosed
WO-2002011883-A1 CATALYST FOR AROMATIC C-O, C-N, and C-C BOND FORMATION YALE UNIVERSITY (US) 2002-02-14 WO disclosed
EP-0027679-B1 SUBSTITUTED-5-((7-CHLORO-4-QUINOLINYL)AMINO)-3-(AMINO-METHYL)-(1,1'-BIPHENYL)-2-OL COMPOUNDS; PROCESSES FOR THEIR PRODUCTION; AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE COMPOUNDS WARNER-LAMBERT COMPANY (US) 1983-08-10 EP disclosed
EP-0027679-A2 Substituted-5-((7-chloro-4-quinolinyl)amino)-3-(amino-methyl)-(1,1'-biphenyl)-2-ol compounds; processes for their production; and pharmaceutical compositions containing the compounds WARNER-LAMBERT COMPANY (US) 1981-04-29 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050256167-A1 Preparation and use of imidazole derivatives for treatment of obesity GPR119, GIPR, PGC SLC6A4 846/4885SLC6A3 592/4885PTPRC 2474/4885
US-20160155952-A1 COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME TMEM109, USE1, TRPC1 SLC6A4 2628/4885SLC6A3 2856/4885PTPRC 4632/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.