Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | CHKA | P35790 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 8/20 | 0.39 |
| ▸ | ACHE | P22303 | 8/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL50943 | 0.98 | HTT (0.53) | HTTCHKABCHEACHEMEN1 | |
| SCHEMBL19946631 | 0.84 | MEN1 (0.54) | HTTCHKABCHEACHEMEN1 | |
| Hydrochloric Acid SCHEMBL29538521 | 0.83 | MEN1 (0.52) | HTTCHKABCHEACHEMEN1 | |
| SCHEMBL18234751 | 0.81 | HTT (0.70) | HTTCHKABCHEACHEMEN1 | |
| SCHEMBL12533280 | 0.81 | HTT (0.77) | HTTCHKABCHEACHEMEN1 | |
| SCHEMBL25525834 | 0.81 | TP53 (0.41) | HTTCHKABCHEACHEMEN1 | |
| SCHEMBL25525855 | 0.80 | MEN1 (0.42) | HTTCHKAMEN1TP53CYP1A2 | |
| SCHEMBL53656 | 0.79 | HTT (0.57) | HTTCHKABCHEACHEMEN1 | |
| Bromide SCHEMBL25241722 | 0.79 | MEN1 (0.41) | HTTCHKAMEN1TP53CYP1A2 | |
| Bromide SCHEMBL25241723 | 0.79 | MEN1 (0.41) | HTTCHKAMEN1TP53CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210221799-A1 | AGGREGATION-INDUCED EMISSION LUMINOGENS FOR PHOTODYNAMIC THERAPY | THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2021-07-22 | — | — | US | disclosed |
| US-9682970-B2 | Fluorescent compounds and uses thereof | BIOTIUM, INC. (US) | 2017-06-20 | — | — | US | disclosed |
| US-9682970-B2 | Fluorescent compounds and uses thereof | BIOTIUM, INC. (US) | 2017-06-20 | — | — | US | disclosed |
| US-20160024067-A1 | FLUORESCENT COMPOUNDS AND USES THEREOF | BIOTIUM, INC. | 2016-01-28 | — | — | US | disclosed |
| US-20160024067-A1 | FLUORESCENT COMPOUNDS AND USES THEREOF | BIOTIUM, INC. | 2016-01-28 | — | — | US | disclosed |
| US-8357350-B2 | Annulus fibrosus detection in intervertebral discs using molecular imaging agents | GENERAL ELECTRIC COMPANY (US) | 2013-01-22 | — | — | US | disclosed |
| US-8129532-B2 | Amino(oligo)thiophene dyes, preparation thereof, and optical methods of use | THE UNIVERSITY OF CONNECTICUT (US) | 2012-03-06 | — | — | US | disclosed |
| US-20100202965-A1 | ANNULUS FIBROSUS DETECTION IN INTERVERTEBRAL DISCS USING MOLECULAR IMAGING AGENTS | GENERAL ELECTRIC COMPANY (US) | 2010-08-12 | — | — | US | disclosed |
| US-20090042227-A1 | AMINO(OLIGO)THIOPHENE DYES, PREPARATION THEREOF, AND OPTICAL METHODS OF USE | NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR | 2009-02-12 | — | — | US | disclosed |
| US-20090042227-A1 | AMINO(OLIGO)THIOPHENE DYES, PREPARATION THEREOF, AND OPTICAL METHODS OF USE | NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR | 2009-02-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210221799-A1 | AGGREGATION-INDUCED EMISSION LUMINOGENS FOR PHOTODYNAMIC THERAPY | PPOX, APC, ANXA4 | HTT 98/4885CHKA 4357/4885BCHE 4730/4885 |
| US-20090042227-A1 | AMINO(OLIGO)THIOPHENE DYES, PREPARATION THEREOF, AND OPTICAL METHODS OF USE | NLN, NME4, OAT | HTT 1658/4885CHKA 4164/4885BCHE 2103/4885 |
| US-20160024067-A1 | FLUORESCENT COMPOUNDS AND USES THEREOF | POLI, POLL, POLRMT | HTT 218/4885CHKA 2797/4885BCHE 3870/4885 |
| US-20100202965-A1 | ANNULUS FIBROSUS DETECTION IN INTERVERTEBRAL DISCS USING MOLECULAR IMAGING AGENTS | BMP1, TMEM14C, NPPA | HTT 2780/4885CHKA 4508/4885BCHE 4815/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.