SCHEMBL5312459

SCHEMBL5312459

COc1cc(Oc2ccccc2)ccc1N

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.63
CYP3A4 P08684 2/20 0.63
LTA4H P09960 2/20 0.55
SMN1; SMN2 Q16637 2/20 0.53
TDP1 Q9NUW8 2/20 0.52
TSHR P16473 2/20 0.52
HSD17B10 Q99714 1/20 0.52
MAOB P27338 1/20 0.50
ADRA2B P18089 1/20 0.50
PTGS1 P23219 1/20 0.50
MAOA P21397 1/20 0.50
MAPK1 P28482 1/20 0.48
HTT P42858 1/20 0.48
L3MBTL1 Q9Y468 1/20 0.48
GAA P10253 3/20 0.47
MEN1 O00255 2/20 0.47
KMT2A Q03164 2/20 0.47
MITF O75030 1/20 0.47
MAPT P10636 1/20 0.47
GFER P55789 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL272888 0.90 ALDH1A1 (0.76) ALDH1A1CYP3A4SMN1; SMN2TDP1TSHR
SCHEMBL12594105 0.87 ALDH1A1 (0.66) ALDH1A1CYP3A4SMN1; SMN2TDP1TSHR
SCHEMBL31457280 0.87 ALDH1A1 (0.66) ALDH1A1CYP3A4SMN1; SMN2TDP1TSHR
SCHEMBL30368 0.86 ALDH1A1 (0.70) ALDH1A1CYP3A4SMN1; SMN2TDP1TSHR
SCHEMBL29764021 0.86 ALDH1A1 (0.70) ALDH1A1CYP3A4SMN1; SMN2TDP1TSHR
SCHEMBL5013387 0.86 MAOA (0.56) ALDH1A1CYP3A4LTA4HSMN1; SMN2TSHR
SCHEMBL28932084 0.86 GAA (0.64) ALDH1A1CYP3A4TDP1TSHRHSD17B10
SCHEMBL1961773 0.85 ALDH1A1 (0.63) ALDH1A1CYP3A4LTA4HSMN1; SMN2TDP1
SCHEMBL3045451 0.85 ALDH1A1 (0.63) ALDH1A1CYP3A4LTA4HSMN1; SMN2TDP1
SCHEMBL5583756 0.85 ALDH1A1 (0.63) ALDH1A1CYP3A4SMN1; SMN2TDP1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250214948-A1 TRIAZINE DERIVATIVES FOR TREATING DISEASES RELATING TO NEUROTROPHINS AlzeCure Pharma AB (SE) 2025-07-03 US disclosed
CN-111819172-B Triazine derivatives for the treatment of neurotrophin related diseases 阿泽克制药公司 2024-02-06 CN disclosed
EP-3759088-B1 TRIAZINE DERIVATIVES FOR TREATING DISEASES RELATING TO NEUROTROPHINS AlzeCure Pharma AB (SE) 2023-01-25 EP disclosed
US-20220306589-A1 TRIAZINE DERIVATIVES FOR TREATING DISEASES RELATING TO NEUROTROPHINS AlzeCure Pharma AB (SE) 2022-09-29 US disclosed
CN-114846080-A Thermoplastic molding compositions containing polyalkylene terephthalates 巴斯夫欧洲公司 2022-08-02 CN disclosed
US-11352332-B2 Triazine derivatives for treating diseases relating to neurotrophins AlzeCure Pharma AB (SE) 2022-06-07 US disclosed
US-20210403456-A1 HETEROCYCLIC COMPOUNDS FOR THE TREATMENT OF EPILEPSY OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2021-12-30 US disclosed
CN-111234219-B Polyimide precursor, polyimide having crosslinked structure, and method for producing same 宇部兴产株式会社 2021-05-28 CN disclosed
CN-108137806-B Polyimide precursor, polyimide having crosslinked structure, and method for producing same 宇部兴产株式会社 2021-05-28 CN disclosed
CN-111205459-B Polyimide precursor, polyimide having crosslinked structure, and method for producing same 宇部兴产株式会社 2021-05-28 CN disclosed
WO-2015086636-A1 INHIBITORS OF BRUTON'S TYROSINE KINASE F. HOFFMANN-LA ROCHE AG (CH) 2015-06-18 WO disclosed
WO-2007056215-A9 N-ARYL-THIENOPYRIMIDIN-4-AMINES AND THE USE THEREOF CYTOVIA INC (US) 2007-09-13 WO disclosed
WO-2007056215-A2 N-ARYL-THIENOPYRIMIDIN-4-AMINES AND THE USE THEREOF CYTOVIA, INC. (US) 2007-05-18 WO disclosed
US-20070099877-A1 N-aryl-thienopyrimidin-4-amines and analogs as activators of caspases and inducers of apoptosis and the use thereof CYTOVIA, INC. (US) 2007-05-03 US disclosed
US-7183278-B1 Picolinamide derivative and harmful organism control agent comprising said picolinamide derivative as active component MEIJI SEIKA KAISHA, LTD. (JP) 2007-02-27 US disclosed
EP-1134214-A1 PICOLINAMIDE DERIVATIVES AND PEST CONTROLLERS CONTAINING THE SAME AS THE ACTIVE INGREDIENT MEIJI SEIKA KAISHA LTD. (JP) 2001-09-19 EP disclosed
EP-0103541-B1 ANTHRAQUINONE DYES, THEIR PREPARATION AND USE CIBA-GEIGY AG (CH) 1989-07-19 EP disclosed
US-4501592-A Anthraquinone dyes, process for their preparation, and use thereof CIBA-GEIGY CORPORATION (US) 1985-02-26 US disclosed
EP-0103541-A2 Anthraquinone dyes, their preparation and use CIBA-GEIGY AG (CH) 1984-03-21 EP disclosed
US-3947477-A Process for the preparation of aminohydroxyanthraquinones BAYER AKTIENGESELLSCHAFT (DT) 1976-03-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220306589-A1 TRIAZINE DERIVATIVES FOR TREATING DISEASES RELATING TO NEUROTROPHINS NTRK2, BDNF, NGF ALDH1A1 2560/4885CYP3A4 4531/4885LTA4H 2344/4885
US-20250214948-A1 TRIAZINE DERIVATIVES FOR TREATING DISEASES RELATING TO NEUROTROPHINS NTRK2, BDNF, NGF ALDH1A1 2560/4885CYP3A4 4531/4885LTA4H 2344/4885
US-20210403456-A1 HETEROCYCLIC COMPOUNDS FOR THE TREATMENT OF EPILEPSY SLC6A11, SCN1A, SCN1B ALDH1A1 288/4885CYP3A4 247/4885LTA4H 1630/4885
US-20070099877-A1 N-aryl-thienopyrimidin-4-amines and analogs as activators of caspases and inducers of apoptosis and the use thereof CASP4, CASP3, API5 ALDH1A1 1132/4885CYP3A4 344/4885LTA4H 870/4885
US-11352332-B2 Triazine derivatives for treating diseases relating to neurotrophins NTRK2, BDNF, NGF ALDH1A1 2164/4885CYP3A4 4426/4885LTA4H 2245/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.