Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPBWR1 | P48145 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | IDH1 | O75874 | 1/20 | 0.36 |
| ▸ | CMA1 | P23946 | 1/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
| ▸ | BAD | Q92934 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5327085 | 0.81 | PDE10A (0.42) | HTTCYP2C9SMN1; SMN2ALDH1A1 | |
| SCHEMBL5325697 | 0.80 | RAD51 (0.40) | HTTCYP2C9SMN1; SMN2PTGS2 | |
| SCHEMBL5330439 | 0.79 | LMNA (0.44) | HTTCYP2C9TP53SMN1; SMN2ALDH1A1 | |
| SCHEMBL5331474 | 0.79 | PTGS2 (0.38) | HTTCYP2C9SMN1; SMN2PTGS2 | |
| SCHEMBL5328955 | 0.78 | TP53 (0.49) | CMA1TP53POLB | |
| SCHEMBL5324677 | 0.78 | RGS4 (0.46) | PTGS2 | |
| SCHEMBL5323331 | 0.76 | RGS4 (0.48) | HTTTP53SMN1; SMN2ALDH1A1POLB | |
| SCHEMBL14624160 | 0.76 | HTT (0.35) | HTTCYP2C9SMN1; SMN2PTGS2POLB | |
| SCHEMBL5297375 | 0.76 | MEN1 (0.42) | HTTCYP2C9SMN1; SMN2PTGS2ALDH1A1 | |
| SCHEMBL5326545 | 0.76 | PTGS2 (0.39) | HTTCYP2C9SMN1; SMN2PTGS2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007007161-A2 | NOVEL BIO-ACTIVE DERIVATIVES | ORCHID RESEARCH LABORATORIES LIMITED (IN) | 2007-01-18 | — | — | WO | claimed |
| WO-2007007161-A2 | NOVEL BIO-ACTIVE DERIVATIVES | ORCHID RESEARCH LABORATORIES LIMITED (IN) | 2007-01-18 | — | — | WO | disclosed |
| WO-2007007161-A2 | NOVEL BIO-ACTIVE DERIVATIVES | ORCHID RESEARCH LABORATORIES LIMITED (IN) | 2007-01-18 | — | — | WO | disclosed |