Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.44 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | NOX4 | Q9NPH5 | 5/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | GNRHR | P30968 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | AR | P10275 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CYBB | P04839 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5327085 | 0.83 | PDE10A (0.42) | RAB9ASMN1; SMN2ALDH1A1CYP2C9HTT | |
| SCHEMBL5325697 | 0.81 | RAD51 (0.40) | LMNANPC1RAB9ASMN1; SMN2CYP2C9 | |
| SCHEMBL5331474 | 0.80 | PTGS2 (0.38) | LMNASMN1; SMN2KDM4ECYP2C9HTT | |
| SCHEMBL5326415 | 0.79 | NPBWR1 (0.39) | TP53SMN1; SMN2ALDH1A1CYP2C9HTT | |
| SCHEMBL5324677 | 0.78 | RGS4 (0.46) | LMNANPC1RAB9ANOX4MAPK1 | |
| SCHEMBL5323606 | 0.77 | LMNA (0.34) | LMNANPC1RAB9ASMN1; SMN2CYP2C9 | |
| SCHEMBL5323331 | 0.77 | RGS4 (0.48) | LMNATP53RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL5297375 | 0.77 | MEN1 (0.42) | LMNASMN1; SMN2ALDH1A1KDM4ECYP2C9 | |
| SCHEMBL14624160 | 0.77 | HTT (0.35) | LMNANPC1RAB9ASMN1; SMN2CYP2C9 | |
| SCHEMBL5326545 | 0.77 | PTGS2 (0.39) | LMNASMN1; SMN2ALDH1A1KDM4ECYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007007161-A2 | NOVEL BIO-ACTIVE DERIVATIVES | ORCHID RESEARCH LABORATORIES LIMITED (IN) | 2007-01-18 | — | — | WO | claimed |
| WO-2007007161-A2 | NOVEL BIO-ACTIVE DERIVATIVES | ORCHID RESEARCH LABORATORIES LIMITED (IN) | 2007-01-18 | — | — | WO | disclosed |
| WO-2007007161-A2 | NOVEL BIO-ACTIVE DERIVATIVES | ORCHID RESEARCH LABORATORIES LIMITED (IN) | 2007-01-18 | — | — | WO | disclosed |