Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 3/20 | 0.47 |
| ▸ | DRD4 | P21917 | 3/20 | 0.47 |
| ▸ | DRD3 | P35462 | 3/20 | 0.47 |
| ▸ | HTR6 | P50406 | 8/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CHIA | Q9BZP6 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5336199 | 0.91 | HTR6 (0.50) | DRD2DRD4DRD3HTR6CHRNA7 | |
| SCHEMBL5337329 | 0.86 | DRD2 (0.44) | DRD2DRD4DRD3HTR6CHRNA7 | |
| SCHEMBL5333822 | 0.82 | MAPT (0.45) | DRD2DRD4DRD3HTR6CHRNA7 | |
| SCHEMBL5334580 | 0.78 | ALDH1A1 (0.44) | DRD2DRD4DRD3HTR6SMN1; SMN2 | |
| SCHEMBL5329261 | 0.77 | HTR6 (0.49) | DRD2DRD4DRD3HTR6CHRNA7 | |
| SCHEMBL5335447 | 0.76 | DRD2 (0.50) | DRD2DRD4DRD3HTR6CHRNA7 | |
| SCHEMBL5335240 | 0.74 | ALDH1A1 (0.44) | DRD2DRD4DRD3HTR6DDR1 | |
| SCHEMBL5335619 | 0.73 | MAPT (0.45) | DRD2DRD4DRD3HTR6CHRNA7 | |
| SCHEMBL5333018 | 0.72 | DDR1 (0.43) | HTR6DDR1KMT2AMEN1KDM4E | |
| SCHEMBL5330544 | 0.72 | HTR6 (0.43) | DRD2DRD4DRD3HTR6SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007046112-A1 | ARYLTHIOETHER TRYPTAMINE DERIVATIVES AS FUNCTIONAL 5-HT6 LIGANDS | SUVEN LIFE SCIENCES INC. (IN) | 2007-04-26 | — | — | WO | claimed |
| WO-2007046112-A1 | ARYLTHIOETHER TRYPTAMINE DERIVATIVES AS FUNCTIONAL 5-HT6 LIGANDS | SUVEN LIFE SCIENCES INC. (IN) | 2007-04-26 | — | — | WO | disclosed |