Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 2/20 | 0.49 |
| ▸ | MGLL | Q99685 | 2/20 | 0.49 |
| ▸ | EGFR | P00533 | 1/20 | 0.49 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.46 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.45 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.44 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5339818 | 0.85 | NOTUM (0.57) | ROCK2MGLLEGFRERBB2POLB | |
| SCHEMBL4202829 | 0.80 | TP53 (0.52) | ROCK2MGLLPOLBNPC1RAB9A | |
| SCHEMBL6097584 | 0.80 | ROCK2 (0.48) | ROCK2MGLLEGFRERBB2POLB | |
| SCHEMBL30207797 | 0.74 | MGLL (0.65) | ROCK2MGLLPOLBNPC1RAB9A | |
| SCHEMBL4432278 | 0.74 | MGLL (0.65) | ROCK2MGLLPOLBNPC1RAB9A | |
| SCHEMBL5342407 | 0.73 | ACLY (0.45) | NPC1RAB9AHDAC8P2RX3 | |
| SCHEMBL16406930 | 0.72 | ACSS2 (0.46) | NPC1RAB9AALDH1A1MAPT | |
| SCHEMBL2746902 | 0.72 | MGLL (0.62) | ROCK2MGLLPOLBNPC1RAB9A | |
| SCHEMBL12058848 | 0.72 | POLB (0.65) | ROCK2MGLLPOLBALDH1A1MAPT | |
| SCHEMBL7836906 | 0.72 | ADORA2B (0.57) | ROCK2MGLLPOLBNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007088478-A1 | INDAZOLE OXAZOLIDINONES AS ANTIBACTERIAL AGENTS | PFIZER PRODUCTS INC. (US) | 2007-08-09 | — | — | WO | disclosed |