Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP14 | P50281 | 4/20 | 0.35 |
| ▸ | MMP8 | P22894 | 3/20 | 0.35 |
| ▸ | MMP9 | P14780 | 3/20 | 0.34 |
| ▸ | MMP13 | P45452 | 3/20 | 0.34 |
| ▸ | MMP1 | P03956 | 2/20 | 0.34 |
| ▸ | MMP3 | P08254 | 2/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.32 |
| ▸ | PDE2A | O00408 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | CCR6 | P51684 | 2/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5337131 | 0.71 | SLC6A4 (0.34) | MMP9MMP1MMP3SLC6A4SLC6A3 | |
| SCHEMBL5337780 | 0.70 | MMP8 (0.41) | MMP14MMP8MMP9MMP13MMP1 | |
| SCHEMBL27680758 | 0.68 | SLC6A4 (0.37) | SLC6A4SLC6A3SLC6A2EPHX2HRH3 | |
| SCHEMBL5474229 | 0.64 | CTSS (0.37) | SLC6A4SLC6A3SLC6A2EPHX2 | |
| SCHEMBL5412391 | 0.64 | SLC6A4 (0.36) | SLC6A4SLC6A3SLC6A2HTR2CEPHX2 | |
| SCHEMBL5449428 | 0.63 | FPR2 (0.39) | SLC6A4SLC6A3SLC6A2EPHX2HRH3 | |
| SCHEMBL5379847 | 0.61 | MMP2 (0.41) | MMP14MMP8MMP9MMP13MMP1 | |
| SCHEMBL28778792 | 0.59 | SLC6A4 (0.46) | SLC6A4SLC6A3SLC6A2HTR2CCCR6 | |
| SCHEMBL28955963 | 0.59 | MMP2 (0.44) | MMP8MMP9EPHX2MMP2HDAC1 | |
| SCHEMBL656498 | 0.58 | SLC6A2 (0.38) | SLC6A4SLC6A3SLC6A2HTR2CEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1771421-A1 | N-HYDROXYAMIDE DERIVATIVES AND USE THEREOF | Applied Research Systems ARS Holding N.V. (AN) | 2007-04-11 | — | — | EP | claimed |
| WO-2006010751-A1 | N-HYDROXYAMIDE DERIVATIVES AND USE THEREOF | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2006-02-02 | — | — | WO | claimed |