SCHEMBL5344846

SCHEMBL5344846

CC[Si](OCCOC)(OCCOC)c1ccccc1

nearest known ligand 0.38

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CA2 P00918 1/20 0.38
TSHR P16473 2/20 0.35
KCNH3 Q9ULD8 2/20 0.33
ALDH1A1 P00352 3/20 0.32
POLB P06746 1/20 0.32
MEN1 O00255 2/20 0.32
KMT2A Q03164 2/20 0.32
HPGD P15428 2/20 0.31
LMNA P02545 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
MAPK1 P28482 1/20 0.31
MPO P05164 1/20 0.30
NCF1 P14598 1/20 0.30
TLR7 Q9NYK1 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL706072 0.84 LMNA (0.37) ALDH1A1MEN1KMT2AHPGDLMNA
SCHEMBL706387 0.81 LTA4H (0.44) TSHRALDH1A1TDP1MAPK1
SCHEMBL115876 0.79 LTA4H (0.34) TSHRALDH1A1HPGD
SCHEMBL19809337 0.79 LMNA (0.34) ALDH1A1MEN1KMT2AHPGDLMNA
SCHEMBL19809285 0.79 LTA4H (0.44) TSHRALDH1A1LMNAMAPK1
SCHEMBL1902441 0.79 LMNA (0.34) ALDH1A1MEN1KMT2AHPGDLMNA
SCHEMBL19356701 0.78 DUT (0.41) CA2TSHRKCNH3ALDH1A1POLB
SCHEMBL5363348 0.78 CA2 (0.41) CA2TSHRKCNH3ALDH1A1POLB
SCHEMBL393946 0.78 CA2 (0.41) CA2TSHRKCNH3ALDH1A1POLB
SCHEMBL15643142 0.78 CA2 (0.37) CA2POLBTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7171750-B2 Method of producing a torsional damper NOK CORPORATION (JP) 2007-02-06 US disclosed
EP-1557586-B1 METHOD OF PRODUCING TORTIONAL DAMPER NOK CORP (JP) 2006-11-02 EP disclosed
EP-1557586-A1 METHOD OF PRODUCING TORTIONAL DAMPER Nok Corporation (JP) 2005-07-27 EP disclosed
US-20050116401-A1 Method of producing tortional damper NOK CORPORATION (JP) 2005-06-02 US disclosed