SCHEMBL535680

SCHEMBL535680

O=C(O)C=Cc1cn([C@H]2C[C@H](O)[C@@H](CO)O2)c(=O)[nH]c1=O

nearest known ligand 0.77

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TK1 P04183 3/20 0.77
CYP1A2 P05177 1/20 0.77
CYP3A4 P08684 1/20 0.77
TSHR P16473 1/20 0.77
BLM P54132 1/20 0.77
PMP22 Q01453 1/20 0.77
NPSR1 Q6W5P4 1/20 0.77
LMNA P02545 2/20 0.64
SMN1; SMN2 Q16637 2/20 0.64
ALOX12 P18054 1/20 0.60
ADRA1A P35348 1/20 0.60
TK2 O00142 1/20 0.59
TYMS P04818 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21316832 1.00 TK1 (0.77) TK1CYP1A2CYP3A4TSHRBLM
SCHEMBL887786 1.00 TK1 (0.77) TK1CYP1A2CYP3A4TSHRBLM
SCHEMBL5982137 1.00 TK1 (0.77) TK1CYP1A2CYP3A4TSHRBLM
SCHEMBL2922785 1.00 TK1 (0.77) TK1CYP1A2CYP3A4TSHRBLM
SCHEMBL887635 1.00 TK1 (0.77) TK1CYP1A2CYP3A4TSHRBLM
SCHEMBL13030268 1.00 TK1 (0.77) TK1CYP1A2CYP3A4TSHRBLM
SCHEMBL887788 1.00 TK1 (0.77) TK1CYP1A2CYP3A4TSHRBLM
SCHEMBL535679 1.00 TK1 (0.77) TK1CYP1A2CYP3A4TSHRBLM
SCHEMBL15457036 0.90 TK1 (0.75) TK1CYP1A2CYP3A4TSHRBLM
SCHEMBL12883747 0.90 TK1 (0.75) TK1CYP1A2CYP3A4TSHRBLM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 148 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115260261-B Preparation method of fluorescent dye modified deoxynucleoside solid phase carrier 苏州诺维康生物科技有限公司 2024-12-13 CN claimed
CN-115260261-A Preparation method of deoxynucleoside solid-phase carrier modified by fluorescent dye 苏州诺维康生物科技有限公司 2022-11-01 CN claimed
US-12584168-B2 Sample preparation method OXFORD NANOPORE TECHNOLOGIES PLC (GB) 2026-03-24 US disclosed
US-20260066042-A1 METHODS AND SYSTEMS FOR HIGH-THROUGHPUT MOLECULAR ANALYSIS OPENTRONS LABWORKS INC (US) 2026-03-05 US disclosed
US-20260036577-A1 SANDWICH ASSAYS IN DROPLETS BIO-RAD LABORATORIES, INC. 2026-02-05 US disclosed
US-20250313889-A1 SAMPLE PREPARATION METHOD OXFORD NANOPORE TECHNOLOGIES PLC (GB) 2025-10-09 US disclosed
US-20250257391-A1 ROLLING CIRCLE AMPLIFICATION COMPRISING CROSSLINKING AND DE-CROSSLINKING 10X GENOMICS, INC. 2025-08-14 US disclosed
US-12359197-B2 Compositions and methods for editing nucleic acids in cells utilizing oligonucleotides ETAGEN PHARMA, INC. (US) 2025-07-15 US disclosed
US-12292440-B2 Sandwich assays in droplets BIO-RAD LABORATORIES, INC. (US) 2025-05-06 US disclosed
WO-2025042899-A2 METHODS FOR IDENTIFYING COMPOUNDS BINDING TO A TARGET MOLECULE USING MIRROR-IMAGING OF THE TARGET MOLECULE X-CHEM, INC. (US) 2025-02-27 WO disclosed
CN-115260261-B Preparation method of fluorescent dye modified deoxynucleoside solid phase carrier 苏州诺维康生物科技有限公司 2024-12-13 CN disclosed
US-20080227104-A1 Replication; hybridization; kits RIKEN (JP) 2008-09-18 US disclosed
EP-1970453-A2 Primer, primer set, and nucleic acid amplification method and mutation detection method using the same Riken (JP) 2008-09-17 EP disclosed
EP-1956089-A1 METHOD FOR DETECTING TARGET NUCLEIC ACID WITH SPECIFIC BASE SEQUENCE AND SET OF NUCLEIC ACIDS FOR DETECTION Japan Science and Technology Agency (JP) 2008-08-13 EP disclosed
US-20060142238-A1 Chemical compounds NuCana plc (GB) 2006-06-29 US disclosed
EP-1646639-A2 NUCLEOTIDE PHOSPHORAMIDATES AS ANTICANCER AGENTS University College Cardiff Consultants, Ltd. (GB) 2006-04-19 EP disclosed
US-20050147973-A1 Immobilized probes GE HEALTHCARE UK LIMITED (GB) 2005-07-07 US disclosed
EP-1520038-A2 DETECTION OF CIRCULARIZED IMMOBILIZED NUCLEIC ACID PROBES Amersham Biosciences UK Limited (GB) 2005-04-06 EP disclosed
WO-2005012327-A2 NUCLEOTIDE PHOSPHORAMIDATES AS ANTICANCER AGENTS UNIVERSITY COLLEGE CARDIFF CONSULTANTS LIMITED (GB) 2005-02-10 WO disclosed
WO-2003083137-A2 DETECTION OF CIRCULARIZED IMMOBILIZED NUCLEIC ACID PROBES AMERSHAM BIOSCIENCES UK LIMITED (GB) 2003-10-09 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12584168-B2 Sample preparation method POLN, POLRMT, POLM TK1 472/4885CYP1A2 4471/4885CYP3A4 3959/4885
US-20080227104-A1 Replication; hybridization; kits PCNA, POLL, RNGTT TK1 300/4885CYP1A2 4851/4885CYP3A4 4220/4885
US-20260066042-A1 METHODS AND SYSTEMS FOR HIGH-THROUGHPUT MOLECULAR ANALYSIS POLRMT, POLL, SARS1 TK1 1713/4885CYP1A2 1193/4885CYP3A4 987/4885
US-20060142238-A1 Chemical compounds NUDT1, DCK, PNP TK1 10/4885CYP1A2 3861/4885CYP3A4 3837/4885
US-20260036577-A1 SANDWICH ASSAYS IN DROPLETS DIS3, S100A4, CHMP4B TK1 2552/4885CYP1A2 4327/4885CYP3A4 2686/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.