Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | RARB | P10826 | 2/20 | 0.38 |
| ▸ | RARG | P13631 | 2/20 | 0.38 |
| ▸ | RARA | P10276 | 1/20 | 0.38 |
| ▸ | RXRA | P19793 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31502587 | 0.83 | ALDH1A1 (0.46) | ALDH1A1GAAMAPTNPSR1ACHE | |
| SCHEMBL3186076 | 0.82 | RARB (0.38) | ALDH1A1GAAMAPTNPSR1ACHE | |
| SCHEMBL19928616 | 0.80 | ALDH1A1 (0.42) | ALDH1A1GAAMAPTNPSR1ACHE | |
| SCHEMBL13779270 | 0.78 | ALDH1A1 (0.41) | ALDH1A1GAAMAPTNPSR1ACHE | |
| SCHEMBL11794721 | 0.78 | ALDH1A1 (0.41) | ALDH1A1GAAMAPTNPSR1ACHE | |
| SCHEMBL4666701 | 0.78 | ALDH1A1 (0.44) | ALDH1A1GAAMAPTNPSR1ACHE | |
| SCHEMBL19227398 | 0.78 | ALDH1A1 (0.41) | ALDH1A1GAAMAPTNPSR1ACHE | |
| SCHEMBL1634590 | 0.78 | ALDH1A1 (0.41) | ALDH1A1GAAMAPTNPSR1ACHE | |
| SCHEMBL13570117 | 0.78 | ALDH1A1 (0.41) | ALDH1A1GAAMAPTNPSR1ACHE | |
| SCHEMBL9328657 | 0.76 | ALDH1A1 (0.38) | ALDH1A1GAAMAPTNPSR1ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240307406-A1 | Device for determining the attitude of a carrier, and associated system for assisting with the piloting of a carrier and determination method | ADVANCED BIODESIGN (FR) | 2024-09-19 | — | — | US | disclosed |
| EP-4284360-A1 | AMINOTHIOLESTER COMPOUND OR DERIVATIVE THEREOF FOR USE AS AN IMMUNOMODULATORY AGENT | Advanced Biodesign (FR) | 2023-12-06 | — | — | EP | disclosed |
| EP-4081499-B1 | FUNCTIONALISATION OF 1,3-ALPHA-DIENES (II) | DSM IP ASSETS BV (NL) | 2023-08-09 | — | — | EP | disclosed |
| US-20220265845-A1 | AMINOTHIOLESTER COMPOUNDS AND USES THEREOF | ADVANCED BIODESIGN (FR) | 2022-08-25 | — | — | US | disclosed |
| WO-2022162196-A1 | AMINOTHIOLESTER COMPOUND OR DERIVATIVE THEREOF FOR USE AS AN IMMUNOMODULATORY AGENT | ADVANCED BIODESIGN (FR) | 2022-08-04 | — | — | WO | disclosed |
| EP-4035666-A1 | AMINOTHIOLESTER COMPOUND OR DERIVATIVE THEREOF FOR USE AS AN IMMUNOMODULATORY AGENT | Advanced Biodesign (FR) | 2022-08-03 | — | — | EP | disclosed |
| EP-3833657-B1 | AMINOTHIOLESTER COMPOUNDS AND USES THEREOF | ADVANCED BIODESIGN (FR) | 2022-07-27 | — | — | EP | disclosed |
| US-20220175700-A1 | VISUAL CYCLE MODULATORS | UNIV CASE WESTERN RESERVE (US) | 2022-06-09 | — | — | US | disclosed |
| CN-114341110-A | Aminothiol ester compound and use thereof | 高级生物设计公司 | 2022-04-12 | — | — | CN | disclosed |
| WO-2021130059-A1 | FUNCTIONALISATION OF 1,3-ALPHA-DIENES (II) | DSM IP ASSETS B.V. (NL) | 2021-07-01 | — | — | WO | disclosed |
| US-20160228419-A1 | SUBSTITUTED QUINOLIZINE DERIVATIVES USEFUL AS HIV INTEGRASE INHIBITORS | MERCK SHARP & DOHME CORP. (US) | 2016-08-11 | — | — | US | disclosed |
| US-20160228419-A1 | SUBSTITUTED QUINOLIZINE DERIVATIVES USEFUL AS HIV INTEGRASE INHIBITORS | MERCK SHARP & DOHME CORP. (US) | 2016-08-11 | — | — | US | disclosed |
| WO-2015048363-A1 | SUBSTITUTED QUINOLIZINE DERIVATIVES USEFUL AS HIV INTEGRASE INHIBITORS | MERCK SHARP & DOHME CORP. (US) | 2015-04-02 | — | — | WO | disclosed |
| US-20070099991-A1 | SELECTIVE RXR LIGANDS | HAFFNER CURT D | 2007-05-03 | — | — | US | disclosed |
| US-20070099991-A1 | SELECTIVE RXR LIGANDS | HAFFNER CURT D | 2007-05-03 | — | — | US | disclosed |
| US-7173134-B2 | Selective RXR ligands | SMITHKLINE BEECHAM CORPORATION (US) | 2007-02-06 | — | — | US | disclosed |
| US-7173134-B2 | Selective RXR ligands | SMITHKLINE BEECHAM CORPORATION (US) | 2007-02-06 | — | — | US | disclosed |
| US-20040198980-A1 | Selective rxr ligands | SMITHKLINE BEECHAM CORPORATION | 2004-10-07 | — | — | US | disclosed |
| EP-1430042-A2 | BICYCLIC HETEROCYCLES AS RXR LIGANDS | SmithKline Beecham Corporation (US) | 2004-06-23 | — | — | EP | disclosed |
| WO-2003027090-A2 | BICYCLIC HETEROCYCLES AS RXR LIGANDS | SMITHKLINE BEECHAM CORPORATION (US) | 2003-04-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220175700-A1 | VISUAL CYCLE MODULATORS | ALDH1A2, UACA, NR2E3 | ALDH1A1 1392/4885GAA 724/4885MAPT 775/4885 |
| US-20040198980-A1 | Selective rxr ligands | RXRA, RXRB, RXRG | ALDH1A1 2289/4885GAA 2654/4885MAPT 4710/4885 |
| US-20220265845-A1 | AMINOTHIOLESTER COMPOUNDS AND USES THEREOF | AADAT, DNPEP, AASDHPPT | ALDH1A1 690/4885GAA 3255/4885MAPT 19/4885 |
| US-20070099991-A1 | SELECTIVE RXR LIGANDS | RXRB, RXRA, RXRG | ALDH1A1 1916/4885GAA 2207/4885MAPT 4680/4885 |
| US-20160228419-A1 | SUBSTITUTED QUINOLIZINE DERIVATIVES USEFUL AS HIV INTEGRASE INHIBITORS | NQO2, CYP3A5, QTRT1 | ALDH1A1 1564/4885GAA 931/4885MAPT 3742/4885 |
| US-20240307406-A1 | Device for determining the attitude of a carrier, and associated system for assisting with the piloting of a carrier and determination method | CD274, CD47, PDCD1LG2 | ALDH1A1 2593/4885GAA 1341/4885MAPT 2174/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.