SCHEMBL53676

SCHEMBL53676

CC(F)SC(=O)SC(C)F

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14156174 0.91 NOS3 (0.32)
SCHEMBL3071643 0.72 NOS3 (0.40) TP53
SCHEMBL20998266 0.67 SLC7A5 (0.36) TP53
SCHEMBL54180 0.67
SCHEMBL4655641 0.67
SCHEMBL14102735 0.67 NOS3 (0.36)
SCHEMBL29063634 0.65
SCHEMBL31323093 0.65 TP53 (0.42) TP53
SCHEMBL7670285 0.63
SCHEMBL21283180 0.63

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11771715-B2 Circular RNA compositions and methods ORNA THERAPEUTICS, INC. (US) 2023-10-03 US disclosed
US-11766449-B2 Circular RNA compositions and methods ORNA THERAPEUTICS, INC. (US) 2023-09-26 US disclosed
US-20230226096-A1 CIRCULAR RNA COMPOSITIONS AND METHODS ORNA THERAPEUTICS, INC. 2023-07-20 US disclosed
US-11680192-B2 Functionalized (co)polymers for adhesive systems TESA SE (DE) 2023-06-20 US disclosed
US-11679120-B2 Circular RNA compositions and methods ORNA THERAPEUTICS, INC. (US) 2023-06-20 US disclosed
US-9765022-B2 Disulfide compounds for delivery of pharmaceutical agents TUFTS UNIVERSITY (US) 2017-09-19 US disclosed
US-20170002236-A1 MULTI-LAYER PRODUCT TESA SE (DE) 2017-01-05 US disclosed
US-20160082126-A1 NANOCOMPLEXES FOR DELIVERY OF SAPORIN UNIV TUFTS (US) 2016-03-24 US disclosed
US-20160009643-A1 DISULFIDE COMPOUNDS FOR DELIVERY OF PHARMACEUTICAL AGENTS TRUSTEES OF TUFTS COLLEGE 2016-01-14 US disclosed
US-8945717-B2 Adhesive material TESA SE (DE) 2015-02-03 US disclosed
US-20100043969-A1 METHOD FOR MOUNTING PRINTING PLATES TO PRINTING CYLINDERS OR SLEEVES WITH ADHESIVE TAPE TESA SE (DE) 2010-02-25 US disclosed
US-20090311473-A1 HEAT-ACTIVATEDLY BONDABLE 2D DIECUTTING ELEMENT TESA AG (DE) 2009-12-17 US disclosed
US-7459499-B2 Pressure-sensitive adhesive based on acrylate block copolymers TESA AG (DE) 2008-12-02 US disclosed
US-7432326-B2 Pressure-sensitive adhesive based on acrylate block copolymers TESA AKTIENGESELLSCHAFT (DE) 2008-10-07 US disclosed
US-7410694-B2 Adhesive TESA AKTIENGESELLSCHAFT (DE) 2008-08-12 US disclosed
US-7402632-B2 2-Component crosslink of end-functionalized polyacrylates TESA AKTIENGESELLSCHAFT (DE) 2008-07-22 US disclosed
US-20080044611-A1 Pressure Sensitive Adhesive Tape for the Adhesion of Printing Plates and Method for the Production Thereof TESA AG (DE) 2008-02-21 US disclosed
US-20070270559-A1 Functionalised Polymers or Contact Adhesive Masses TESA SE (DE) 2007-11-22 US disclosed
US-7271203-B2 Crosslinking of photoiniator-initialized polyacrylates TESA AKTIENGESELLSCHAFT (DE) 2007-09-18 US disclosed
US-20070172684-A1 Adhesive material TESA AG (DE) 2007-07-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11771715-B2 Circular RNA compositions and methods RTCB, HNRNPA1, HNRNPAB TP53 609/4885
US-20160009643-A1 DISULFIDE COMPOUNDS FOR DELIVERY OF PHARMACEUTICAL AGENTS P4HB, PDIA6, PDIA5 TP53 2453/4885
US-20160082126-A1 NANOCOMPLEXES FOR DELIVERY OF SAPORIN SARNP, SAP30BP, SCP2 TP53 408/4885
US-20230226096-A1 CIRCULAR RNA COMPOSITIONS AND METHODS RTCB, HNRNPA1, HNRNPAB TP53 609/4885
US-11679120-B2 Circular RNA compositions and methods RTCB, HNRNPA1, HNRNPAB TP53 609/4885
US-11766449-B2 Circular RNA compositions and methods RTCB, RNGTT, HNRNPAB TP53 595/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.