Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | CES1 | P23141 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | MC4R | P32245 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
| ▸ | ALPL | P05186 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL809458 | 0.84 | CASP3 (0.48) | MAPTRAB9AALDH1A1HSD17B10PKM | |
| SCHEMBL30872008 | 0.84 | CASP3 (0.48) | MAPTRAB9AALDH1A1HSD17B10PKM | |
| SCHEMBL11105056 | 0.82 | KMT2A (0.46) | MEN1KMT2AMAPTRAB9AALDH1A1 | |
| SCHEMBL20503165 | 0.82 | MEN1 (0.52) | MEN1KMT2AMAPTRAB9AALDH1A1 | |
| SCHEMBL28673975 | 0.81 | GSK3B (0.44) | MEN1KMT2AMAPTRAB9AALDH1A1 | |
| SCHEMBL29727795 | 0.81 | MAP2K7 (0.41) | MEN1KMT2AMAPTRAB9AALDH1A1 | |
| SCHEMBL29727850 | 0.80 | MMP2 (0.43) | MEN1KMT2AMAPTALDH1A1HSD17B10 | |
| SCHEMBL16694595 | 0.77 | RAB9A (0.50) | MEN1KMT2AMAPTRAB9AALDH1A1 | |
| SCHEMBL29475759 | 0.77 | RAB9A (0.50) | MEN1KMT2AMAPTRAB9AALDH1A1 | |
| SCHEMBL11450996 | 0.73 | MEN1 (0.40) | MEN1KMT2AMAPTRAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12492220-B2 | Method for the preparation of oligonucleotides | THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING/MCGILL UNIVERSITY (CA) | 2025-12-09 | — | — | US | claimed |
| US-20230192751-A1 | METHOD FOR THE PREPARATION OF OLIGONUCLEOTIDES | THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING/MCGILL UNIV (CA) | 2023-06-22 | — | — | US | claimed |
| US-12492220-B2 | Method for the preparation of oligonucleotides | THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING/MCGILL UNIVERSITY (CA) | 2025-12-09 | — | — | US | disclosed |
| US-20230192751-A1 | METHOD FOR THE PREPARATION OF OLIGONUCLEOTIDES | THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING/MCGILL UNIV (CA) | 2023-06-22 | — | — | US | disclosed |
| US-11548910-B2 | Oligonucleotide production method | NISSAN CHEMICAL CORPORATION (JP) | 2023-01-10 | — | — | US | disclosed |
| CN-110330526-B | Green synthesis method of thiophosphite | 成都理工大学 | 2021-11-26 | — | — | CN | disclosed |
| CN-110330526-A | A kind of green synthesis method of thio phosphinate | 成都理工大学 | 2019-10-15 | — | — | CN | disclosed |
| US-20190169223-A1 | OLIGONUCLEOTIDE PRODUCTION METHOD | NISSAN CHEMICAL CORPORATION (JP) | 2019-06-06 | — | — | US | disclosed |
| EP-3378869-A1 | METHOD FOR PRODUCING OLIGONUCLEOTIDE | Nissan Chemical Corporation (JP) | 2018-09-26 | — | — | EP | disclosed |
| CN-103936805-B | A kind of nucleotide and/or oligonucleotide and preparation method thereof | 昆山市工业技术研究院小核酸生物技术研究所有限责任公司 | 2016-12-28 | — | — | CN | disclosed |
| CN-103936805-A | Nucleotide and/or oligonucleotide and preparation method thereof | KUNSHAN INDUSTRY TECHNOLOGY RES INST SMALL NUCLEIC ACID BIOLOG TECHNOLOGY INST CO LTD | 2014-07-23 | — | — | CN | disclosed |
| EP-1325927-A2 | Synthesis of oligonucleotides | Avecia Limited (GB) | 2003-07-09 | — | — | EP | disclosed |
| US-20030083490-A1 | Solution phase synthesis of oligonucleotides | AVECIA LIMITED | 2003-05-01 | — | — | US | disclosed |
| EP-1003758-B1 | SOLUTION PHASE SYNTHESIS OF OLIGONUCLEOTIDES | AVECIA LTD (GB) | 2003-04-09 | — | — | EP | disclosed |
| US-6506894-B1 | Phosphonation; oxidation in situ with sulfur transfer agent | AVECIA LIMITED (GB) | 2003-01-14 | — | — | US | disclosed |
| US-5879872-A | ANTIFOGGANTS | EASTMAN KODAK COMPANY (US) | 1999-03-09 | — | — | US | disclosed |
| EP-0004320-B1 | 1-SUBSTITUTED-THIOMETHYLTRIAZOLOBENZODIAZEPINES, PREPARATION THEREOF, THEIR USE, AND A PHARMACEUTICAL COMPOSITION | SHIONOGI & CO., LTD. (JP) | 1981-12-16 | — | — | EP | disclosed |
| US-4264499-A | PSYCHOTROPIC AGENTS, ANXIOLYTICS, ANTICONVULSANTS, HYOTICS | SHIONOGI & CO., LTD. (JP) | 1981-04-28 | — | — | US | disclosed |
| US-4231930-A | PSYCHOTROPIC AGENTS, ANXIOLYTICS, ANTICONVULSANTS, HYPNOTICS | SHIONOGI & CO., LTD. (JP) | 1980-11-04 | — | — | US | disclosed |
| EP-0004320-A1 | 1-Substituted-thiomethyltriazolobenzodiazepines, preparation thereof, their use, and a pharmaceutical composition | SHIONOGI & CO., LTD. (JP) | 1979-10-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030083490-A1 | Solution phase synthesis of oligonucleotides | NUDT1, POLR2E, POLRMT | MEN1 2369/4885KMT2A 3491/4885MAPT 1792/4885 |
| US-11548910-B2 | Oligonucleotide production method | RNGTT, OSGEP, PHAX | MEN1 3165/4885KMT2A 2395/4885MAPT 3183/4885 |
| US-20190169223-A1 | OLIGONUCLEOTIDE PRODUCTION METHOD | RNGTT, OSGEP, PHAX | MEN1 3165/4885KMT2A 2395/4885MAPT 3183/4885 |
| US-12492220-B2 | Method for the preparation of oligonucleotides | POLN, POLRMT, POLI | MEN1 3413/4885KMT2A 3340/4885MAPT 3637/4885 |
| US-20230192751-A1 | METHOD FOR THE PREPARATION OF OLIGONUCLEOTIDES | POLN, POLRMT, POLI | MEN1 3413/4885KMT2A 3340/4885MAPT 3637/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.