Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | GLA | P06280 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | CASP1 | P29466 | 2/20 | 0.36 |
| ▸ | CASP7 | P55210 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | CHRNA7 | P36544 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.34 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5382237 | 0.83 | KDM4E (0.36) | ACHEALDH1A1KDM4EGLAHPGD | |
| SCHEMBL14486369 | 0.77 | KDM4E (0.45) | ACHEALDH1A1KDM4EGLAHPGD | |
| SCHEMBL6075955 | 0.73 | HTR1A (0.39) | ACHECYP3A4HTR1A | |
| SCHEMBL6101436 | 0.70 | GRIN2D (0.40) | ACHEALDH1A1KDM4ECHRNA7MEN1 | |
| SCHEMBL25206308 | 0.66 | PTGS2 (0.39) | CASP1CASP7HSD17B10MEN1KMT2A | |
| SCHEMBL6570348 | 0.65 | IMPDH2 (0.39) | ALDH1A1KDM4EHPGDHSD17B10GAA | |
| SCHEMBL5373765 | 0.65 | MAOA (0.58) | KDM4EHSD17B10CYP2C9DRD2DRD3 | |
| SCHEMBL30042409 | 0.65 | HTR2C (0.35) | KDM4EHSD17B10CYP2C9DRD2DRD3 | |
| SCHEMBL15858421 | 0.63 | HTR1A (0.46) | ACHEALDH1A1KDM4EGLAHPGD | |
| SCHEMBL12058460 | 0.62 | LRRK2 (0.43) | DRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7022664-B2 | 1,2 Substituted 2,3-dihydro-1H-5,9 dioxacyclohepta[F]indden-7-ones and 7-substituted benzo[B][1,4]dioxepin-3-ones | GIVAUDAN SA (CH) | 2006-04-04 | — | — | US | claimed |
| US-20030207788-A1 | 1,2 Substituted 2,3-dihydro- 1H-5,9 dioxacyclohepta[F]indden-7-ones and 7-substituted benzo[B][1,4]dioxepin-3 ones | GIVADUAN SA, CHEMIN DE LA PARFUMERIE (CH) | 2003-11-06 | — | — | US | claimed |
| EP-1136481-B1 | 1,2-Substituted 2,3-dihydro-1H-5,9-dioxacyclohepta[f]inden-7-ones and 7-substituted benzo[b][1,4]dioxepin-3-ones | GIVAUDAN SA (CH) | 2002-11-13 | — | — | EP | claimed |
| US-20010044407-A1 | Use in fragrance compositions; marine odor | GIVAUDAN SA (CH) | 2001-11-22 | — | — | US | claimed |
| EP-1136481-A1 | 1,2-Substituted 2,3-dihydro-1H-5,9-dioxacyclohepta[f]inden-7-ones and 7-substituted benzo[b][1,4]dioxepin-3-ones | Givaudan SA (CH) | 2001-09-26 | — | — | EP | claimed |
| US-7235519-B2 | 1,2-substituted 2,3-dehydro-1H-5,9-dioxyacyclohepta[f]inden-7-ones and 7-substituted benzo[b]dioxepin-3-ones | GIVAUDAN SA (CH) | 2007-06-26 | — | — | US | disclosed |
| US-7022664-B2 | 1,2 Substituted 2,3-dihydro-1H-5,9 dioxacyclohepta[F]indden-7-ones and 7-substituted benzo[B][1,4]dioxepin-3-ones | GIVAUDAN SA (CH) | 2006-04-04 | — | — | US | disclosed |
| US-20050288518-A1 | 1,2-Substituted 2,3-dehydro-1H-5,9-dioxyacyclohepta[f]inden-7-ones and 7-substituted benzo[b]dioxepin-3-ones | GIVAUDAN SA (CH) | 2005-12-29 | — | — | US | disclosed |
| US-20030207788-A1 | 1,2 Substituted 2,3-dihydro- 1H-5,9 dioxacyclohepta[F]indden-7-ones and 7-substituted benzo[B][1,4]dioxepin-3 ones | GIVADUAN SA, CHEMIN DE LA PARFUMERIE (CH) | 2003-11-06 | — | — | US | disclosed |
| EP-1136481-B1 | 1,2-Substituted 2,3-dihydro-1H-5,9-dioxacyclohepta[f]inden-7-ones and 7-substituted benzo[b][1,4]dioxepin-3-ones | GIVAUDAN SA (CH) | 2002-11-13 | — | — | EP | disclosed |
| US-20010044407-A1 | Use in fragrance compositions; marine odor | GIVAUDAN SA (CH) | 2001-11-22 | — | — | US | disclosed |
| EP-1136481-A1 | 1,2-Substituted 2,3-dihydro-1H-5,9-dioxacyclohepta[f]inden-7-ones and 7-substituted benzo[b][1,4]dioxepin-3-ones | Givaudan SA (CH) | 2001-09-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030207788-A1 | 1,2 Substituted 2,3-dihydro- 1H-5,9 dioxacyclohepta[F]indden-7-ones and 7-substituted benzo[B][1,4]dioxepin-3 ones | CYP1B1, CYP1A1, CYP4B1 | ACHE 3214/4885ALDH1A1 46/4885KDM4E 873/4885 |
| US-20010044407-A1 | Use in fragrance compositions; marine odor | OPRD1, TRPA1, DBN1 | ACHE 1785/4885ALDH1A1 714/4885KDM4E 1764/4885 |
| US-20050288518-A1 | 1,2-Substituted 2,3-dehydro-1H-5,9-dioxyacyclohepta[f]inden-7-ones and 7-substituted benzo[b]dioxepin-3-ones | CYP1B1, CYP1A1, SULT1E1 | ACHE 2615/4885ALDH1A1 91/4885KDM4E 871/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.