Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.31 |
| ▸ | TUBB | P07437 | 2/20 | 0.31 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.31 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.31 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.31 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.31 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.31 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.31 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.31 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.31 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.31 |
| ▸ | TUBA1C | Q9BQE3 | 2/20 | 0.31 |
| ▸ | TUBB6 | Q9BUF5 | 2/20 | 0.31 |
| ▸ | TUBB2B | Q9BVA1 | 2/20 | 0.31 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5375002 | 0.73 | ACHE (0.38) | HTR1ACYP3A4ACHE | |
| SCHEMBL11695042 | 0.72 | HTR1A (0.53) | HTR1ACYP3A4ACHE | |
| SCHEMBL6101436 | 0.66 | GRIN2D (0.40) | ACHE | |
| SCHEMBL6570348 | 0.65 | IMPDH2 (0.39) | — | |
| SCHEMBL15858421 | 0.63 | HTR1A (0.46) | HTR1ACYP3A4ACHE | |
| SCHEMBL11858996 | 0.62 | HTR1A (0.44) | HTR1ACYP3A4ACHETUBB4ATUBB | |
| SCHEMBL410055 | 0.60 | OPRM1 (0.44) | — | |
| SCHEMBL235690 | 0.60 | MMP12 (0.53) | — | |
| SCHEMBL20921808 | 0.60 | ACHE (0.43) | ACHE | |
| SCHEMBL20921756 | 0.60 | ACHE (0.43) | ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7022664-B2 | 1,2 Substituted 2,3-dihydro-1H-5,9 dioxacyclohepta[F]indden-7-ones and 7-substituted benzo[B][1,4]dioxepin-3-ones | GIVAUDAN SA (CH) | 2006-04-04 | — | — | US | claimed |
| US-20030207788-A1 | 1,2 Substituted 2,3-dihydro- 1H-5,9 dioxacyclohepta[F]indden-7-ones and 7-substituted benzo[B][1,4]dioxepin-3 ones | GIVADUAN SA, CHEMIN DE LA PARFUMERIE (CH) | 2003-11-06 | — | — | US | claimed |
| EP-1136481-B1 | 1,2-Substituted 2,3-dihydro-1H-5,9-dioxacyclohepta[f]inden-7-ones and 7-substituted benzo[b][1,4]dioxepin-3-ones | GIVAUDAN SA (CH) | 2002-11-13 | — | — | EP | claimed |
| US-20010044407-A1 | Use in fragrance compositions; marine odor | GIVAUDAN SA (CH) | 2001-11-22 | — | — | US | claimed |
| EP-1136481-A1 | 1,2-Substituted 2,3-dihydro-1H-5,9-dioxacyclohepta[f]inden-7-ones and 7-substituted benzo[b][1,4]dioxepin-3-ones | Givaudan SA (CH) | 2001-09-26 | — | — | EP | claimed |
| US-7235519-B2 | 1,2-substituted 2,3-dehydro-1H-5,9-dioxyacyclohepta[f]inden-7-ones and 7-substituted benzo[b]dioxepin-3-ones | GIVAUDAN SA (CH) | 2007-06-26 | — | — | US | disclosed |
| US-7235519-B2 | 1,2-substituted 2,3-dehydro-1H-5,9-dioxyacyclohepta[f]inden-7-ones and 7-substituted benzo[b]dioxepin-3-ones | GIVAUDAN SA (CH) | 2007-06-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030207788-A1 | 1,2 Substituted 2,3-dihydro- 1H-5,9 dioxacyclohepta[F]indden-7-ones and 7-substituted benzo[B][1,4]dioxepin-3 ones | CYP1B1, CYP1A1, CYP4B1 | HTR1A 211/4885CYP3A4 64/4885ACHE 3214/4885 |
| US-20010044407-A1 | Use in fragrance compositions; marine odor | OPRD1, TRPA1, DBN1 | HTR1A 353/4885CYP3A4 250/4885ACHE 1785/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.