Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C2 | P08235 | 1/20 | 0.33 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | HTR6 | P50406 | 2/20 | 0.31 |
| ▸ | CYP24A1 | Q07973 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | SMYD2 | Q9NRG4 | 1/20 | 0.30 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.30 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | ABL1 | P00519 | 1/20 | 0.30 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17456530 | 0.83 | ELANE (0.39) | ALDH1A1HSD17B10TDP1HTR6CYP3A4 | |
| SCHEMBL17466333 | 0.81 | HTR6 (0.33) | HTR6ABL1 | |
| SCHEMBL537975 | 0.81 | CA2 (0.33) | PTGS1PTGS2HSD11B1 | |
| SCHEMBL14778859 | 0.77 | KEAP1 (0.38) | KEAP1ALDH1A1HSD17B10TDP1HTR6 | |
| SCHEMBL19197241 | 0.76 | SMYD2 (0.38) | ALDH1A1CYP3A4HTTSMN1; SMN2SMYD2 | |
| SCHEMBL538583 | 0.75 | KEAP1 (0.37) | KEAP1ALDH1A1HSD17B10TDP1HTR6 | |
| SCHEMBL79874 | 0.74 | MAPK1 (0.37) | ALDH1A1CYP3A4HTTSMN1; SMN2SMYD2 | |
| SCHEMBL15888456 | 0.74 | MAPK1 (0.37) | ALDH1A1CYP3A4HTTSMN1; SMN2SMYD2 | |
| SCHEMBL22750792 | 0.74 | KDM4E (0.40) | ALDH1A1CYP3A4HTTSMN1; SMN2SMYD2 | |
| SCHEMBL2057888 | 0.74 | KEAP1 (0.35) | KEAP1ALDH1A1HSD17B10TDP1HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7399845-B2 | 6-modified bicyclic nucleic acid analogs | ISIS PHARMACEUTICALS, INC. (US) | 2008-07-15 | — | — | US | claimed |
| US-20070249049-A1 | 6-MODIFIED BICYCLIC NUCLEIC ACID ANALOGS | FOUNDATION MEDICINE, INC. | 2007-10-25 | — | — | US | claimed |
| US-8716435-B2 | Multibranched polyoxyalkylene compound and producing method thereof | NOF CORPORATION (JP) | 2014-05-06 | — | — | US | disclosed |
| EP-2415800-B1 | HYPERBRANCHED POLYOXYALKYLENE COMPOUND AND METHOD FOR PRODUCING SAME | NOF CORP (JP) | 2013-10-16 | — | — | EP | disclosed |
| CN-102378775-B | Multibranched polyoxyalkylene compound and process for producing the same | NIPPON OIL CORP | 2013-10-09 | — | — | CN | disclosed |
| CN-102378775-A | Multibranched polyoxyalkylene compound and process for producing the same | NOF CORP | 2012-03-14 | — | — | CN | disclosed |
| EP-2415800-A1 | HYPERBRANCHED POLYOXYALKYLENE COMPOUND AND METHOD FOR PRODUCING SAME | NOF Corporation (JP) | 2012-02-08 | — | — | EP | disclosed |
| US-20100261863-A1 | MULTIBRANCHED POLYOXYALKYLENE COMPOUND AND PRODUCING METHOD THEREOF | NOF CORPORATION (JP) | 2010-10-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070249049-A1 | 6-MODIFIED BICYCLIC NUCLEIC ACID ANALOGS | NSUN2, POLRMT, POLM | NR3C2 2274/4885KEAP1 3054/4885ALDH1A1 3471/4885 |
| US-20100261863-A1 | MULTIBRANCHED POLYOXYALKYLENE COMPOUND AND PRODUCING METHOD THEREOF | OPRM1, AOC2, OPRK1 | NR3C2 3305/4885KEAP1 563/4885ALDH1A1 17/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.