Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B1 | P14061 | 3/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 5/20 | 0.41 |
| ▸ | ESR1 | P03372 | 4/20 | 0.38 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | QDPR | P09417 | 5/20 | 0.36 |
| ▸ | ACMSD | Q8TDX5 | 2/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.35 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | MMP3 | P08254 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5387165 | 0.89 | ALOX5 (0.47) | HSD17B1ESR2ESR1QDPRACMSD | |
| SCHEMBL5388046 | 0.86 | ALOX5 (0.39) | HSD17B1ESR2ESR1QDPRALOX5 | |
| SCHEMBL5389243 | 0.85 | GABRA1 (0.45) | HSD17B1ESR2QDPRACMSD | |
| SCHEMBL2719243 | 0.81 | ESR2 (0.45) | HSD17B1ESR2ESR1AR | |
| SCHEMBL503467 | 0.80 | ESR2 (0.41) | HSD17B1ESR2ESR1ARQDPR | |
| SCHEMBL5394780 | 0.78 | ESR2 (0.39) | ESR2QDPRACMSDHSP90AA1HSP90AB1 | |
| SCHEMBL5439557 | 0.77 | ALDH1A1 (0.42) | ESR2ESR1QDPRHSP90AA1HSP90AB1 | |
| SCHEMBL4219995 | 0.74 | HSD17B1 (0.49) | HSD17B1ESR2ESR1ARBACE1 | |
| SCHEMBL503196 | 0.73 | ESR2 (0.62) | ESR2ESR1QDPRMMP3 | |
| SCHEMBL3953461 | 0.73 | HSD17B1 (0.71) | HSD17B1ESR2ESR1ARBACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7196232-B2 | 4,4′-dihydroxyphenyl bicyclohexenes | HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) | 2007-03-27 | — | — | US | claimed |
| US-20060129001-A1 | Novel 4,4'-dihydroxyphenyl bicyclohexenes | HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) | 2006-06-15 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060129001-A1 | Novel 4,4'-dihydroxyphenyl bicyclohexenes | DBF4, DCUN1D4, SDC4 | HSD17B1 2133/4885ESR2 2548/4885ESR1 1397/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.