Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 3/20 | 0.45 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.45 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | QDPR | P09417 | 5/20 | 0.34 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.32 |
| ▸ | THRA | P10827 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | ACMSD | Q8TDX5 | 2/20 | 0.31 |
| ▸ | NAMPT | P43490 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5382437 | 0.85 | HSD17B1 (0.46) | ESR2QDPRHSD17B1ACMSD | |
| SCHEMBL3816888 | 0.83 | ESR2 (0.42) | GABRA1GABRB2ESR2QDPR | |
| SCHEMBL5387165 | 0.82 | ALOX5 (0.47) | GABRA1GABRB2ESR2QDPRHSD17B1 | |
| SCHEMBL5394780 | 0.80 | ESR2 (0.39) | GABRA1GABRB2ESR2QDPRTHRA | |
| SCHEMBL5388046 | 0.80 | ALOX5 (0.39) | ESR2QDPRHSD17B1 | |
| SCHEMBL503467 | 0.77 | ESR2 (0.41) | ESR2QDPRHSD17B1ACMSD | |
| SCHEMBL5439557 | 0.73 | ALDH1A1 (0.42) | ESR2QDPR | |
| SCHEMBL503196 | 0.70 | ESR2 (0.62) | ESR2QDPR | |
| SCHEMBL3816880 | 0.70 | GABRA1 (0.59) | GABRA1GABRB2ESR2HSD17B1 | |
| SCHEMBL2719243 | 0.68 | ESR2 (0.45) | ESR2HSD17B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7196232-B2 | 4,4′-dihydroxyphenyl bicyclohexenes | HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) | 2007-03-27 | — | — | US | claimed |
| US-20060129001-A1 | Novel 4,4'-dihydroxyphenyl bicyclohexenes | HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) | 2006-06-15 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060129001-A1 | Novel 4,4'-dihydroxyphenyl bicyclohexenes | DBF4, DCUN1D4, SDC4 | GABRA1 1572/4885GABRB2 1845/4885ESR2 2548/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.