Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | HRH1 | P35367 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | STAT6 | P42226 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19399106 | 0.84 | NPSR1 (0.44) | RAB9AALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL9173207 | 0.82 | ALDH1A1 (0.44) | HTR2AHRH1ALDH1A1KDM4E | |
| SCHEMBL28986023 | 0.80 | ADRA2A (0.50) | RAB9APOLBHTTNPSR1L3MBTL1 | |
| SCHEMBL6055320 | 0.80 | PPARG (0.49) | RAB9ATP53TSHRPOLBHTT | |
| SCHEMBL30669716 | 0.80 | PPARG (0.49) | RAB9ATP53TSHRPOLBHTT | |
| SCHEMBL8770873 | 0.80 | AGTR1 (0.47) | RAB9ATP53TSHRPOLBHTT | |
| SCHEMBL6055141 | 0.79 | PPARG (0.55) | RAB9ATSHR | |
| SCHEMBL3916474 | 0.79 | RAB9A (0.44) | RAB9ATP53TSHRPOLBHTT | |
| SCHEMBL3916470 | 0.79 | RAB9A (0.44) | RAB9ATP53TSHRPOLBHTT | |
| SCHEMBL10514096 | 0.79 | RAB9A (0.44) | RAB9ATP53TSHRPOLBHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE39593-E1 | 1-phenyl-3-dimethylaminopropane compounds with a pharmacological effects | GRUENENTHAL GMBH (DE) | 2007-04-24 | — | — | US | disclosed |
| US-6344558-B1 | ANALGESICS | GRUENTHAL GMBH (DE) | 2002-02-05 | — | — | US | disclosed |
| US-20020010178-A1 | 1-phenyl-3-dimethylaminopropane compounds with a pharmacological effect | GRUENENTHAL GMBH | 2002-01-24 | — | — | US | disclosed |
| CN-1077566-C | 1-phenyl-3-dimethylaminopropane compounds with a pharmacological effect | GRUENENTHAL GMBH (DE) | 2002-01-09 | — | — | CN | disclosed |
| US-6248737-B1 | ANALGESICS | GRUENENTHAL GMBH (DE) | 2001-06-19 | — | — | US | disclosed |
| CN-1125221-A | 1-phenyl-3-dimethylaminopropane compounds with a pharmacological effect | GRUENENTHAL GMBH (DE) | 1996-06-26 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020010178-A1 | 1-phenyl-3-dimethylaminopropane compounds with a pharmacological effect | OPRM1, OPRK1, OPRD1 | HTR7 165/4885HTR2A 164/4885HRH1 686/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.