Edetic Acid

Edetic Acid

SCHEMBL5403891

N.N.O.O=C(O)CN(CCN(CC(=O)O)CC(=O)O)CC(=O)O

nearest known ligand 0.88

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO

The experimentally established mechanism targets of Edetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACE known ✓ P12821 1/20 0.88
CHRM2 known ✓ P08172 1/20 0.82
ADRA2A known ✓ P08913 1/20 0.82
SLC6A2 known ✓ P23975 1/20 0.82
SLC6A4 known ✓ P31645 1/20 0.82
ADRA1A known ✓ P35348 1/20 0.82
DRD3 known ✓ P35462 1/20 0.82
SLC6A3 known ✓ Q01959 1/20 0.82
TDP1 Q9NUW8 2/20 0.88
EYA2 O00167 1/20 0.88
APP P05067 1/20 0.88
BLM P54132 2/20 0.82
PMP22 Q01453 2/20 0.82
KDM4E B2RXH2 2/20 0.82
ALOX15 P16050 2/20 0.82
TSHR P16473 2/20 0.82
LMNA P02545 1/20 0.82
DRD1 P21728 1/20 0.82
CYP2C19 P33261 1/20 0.82
HRH3 Q9Y5N1 1/20 0.82

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Edetic Acid SCHEMBL3973738 1.00 TDP1 (0.88) TDP1EYA2APPACEBLM
Edetic Acid SCHEMBL10415818 1.00 TDP1 (0.88) TDP1EYA2APPACEBLM
Edetic Acid SCHEMBL5718897 1.00 TDP1 (0.88) TDP1EYA2APPACEBLM
Edetic Acid SCHEMBL3973748 1.00 TDP1 (0.88) TDP1EYA2APPACEBLM
Edetic Acid SCHEMBL8361892 1.00 TDP1 (0.88) TDP1EYA2APPACEBLM
Edetic Acid SCHEMBL9864736 0.97 TDP1 (0.82) TDP1EYA2APPACEBLM
Edetic Acid SCHEMBL8658392 0.97 TDP1 (0.82) TDP1EYA2APPACEBLM
Edetic Acid SCHEMBL8044889 0.97 TDP1 (0.82) TDP1EYA2APPACEBLM
Edetic Acid SCHEMBL9751865 0.97 TDP1 (0.82) TDP1EYA2APPACEBLM
Edetic Acid SCHEMBL9796993 0.97 TDP1 (0.82) TDP1EYA2APPACEBLM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115976586-A Positive and negative pulse electrolytic nickel-tungsten alloy solution, preparation method, electroplating method and nickel-tungsten alloy coating 昆山一鼎工业科技有限公司 2023-04-18 CN claimed
US-6926936-B2 Ink-jet recording sheet with improved ozone resistance FELIX SCHOELLER JR. FOTO-UND SPEZIALPAPIERE GMBH & CO. KG (DE) 2005-08-09 US claimed
US-20030219611-A1 Ink-jet recording sheet with improved ozone resistance FELIX SCHOELLER JR. FOTO-UND SPEZIALPAPIERE GMBH & CO. KG 2003-11-27 US claimed
EP-1364803-A1 Ink-Jet recording material with improved ozone resistance Felix Schoeller jr Foto- und Spezialpapiere GmbH & Co. KG (DE) 2003-11-26 EP claimed
US-12292363-B2 Method for preparing biological material having excellent light-transmitting property RIKEN (JP) 2025-05-06 US disclosed
EP-4340056-A1 POSITIVE ELECTRODE MIXTURE, POSITIVE ELECTRODE AND SECONDARY BATTERY Daikin Industries, Ltd. (JP) 2024-03-20 EP disclosed
US-20240088381-A1 POSITIVE ELECTRODE MIXTURE, POSITIVE ELECTRODE AND SECONDARY BATTERY DAIKIN INDUSTRIES, LTD. (JP) 2024-03-14 US disclosed
EP-4336584-A1 POSITIVE ELECTRODE MIXTURE, POSITIVE ELECTRODE AND SECONDARY BATTERY Daikin Industries, Ltd. (JP) 2024-03-13 EP disclosed
US-20240079595-A1 POSITIVE ELECTRODE MIXTURE, POSITIVE ELECTRODE AND SECONDARY BATTERY DAIKIN INDUSTRIES, LTD. (JP) 2024-03-07 US disclosed
CN-117202784-A Antimicrobial compounds and solutions, uses thereof, and methods of making the same 宇天新技术有限公司 2023-12-08 CN disclosed
CN-115976586-A Positive and negative pulse electrolytic nickel-tungsten alloy solution, preparation method, electroplating method and nickel-tungsten alloy coating 昆山一鼎工业科技有限公司 2023-04-18 CN disclosed
CN-115452930-A Method for simultaneously determining 12 heavy metal elements in high-salt food 汕头海关技术中心 2022-12-09 CN disclosed
US-20220381657-A1 METHOD FOR PREPARING BIOLOGICAL MATERIAL HAVING EXCELLENT LIGHT-TRANSMITTING PROPERTY RIKEN (JP) 2022-12-01 US disclosed
WO-2022167909-A1 ANTIMICROBIAL COMPOUNDS AND SOLUTIONS, USES THEREOF AND METHODS OF MAKING THE SAME UT INNOVATION LIMITED (CN) 2022-08-11 WO disclosed
CN-103936087-B Mixed blue-green algae treating agent WUHU KAIAOER ENVIRONMENTAL PROT TECHNOLOGY CO LTD 2015-04-08 CN disclosed
CN-103936087-A Mixed blue-green algae treating agent and preparation method thereof WUHU KAIAOER ENVIRONMENTAL PROT TECHNOLOGY CO LTD 2014-07-23 CN disclosed
US-7196211-B2 Hafnium-containing material for film formation, method for producing the same, and method for producing hafnium-containing thin film using the same MITSUBISHI MATERIALS CORPORATION (JP) 2007-03-27 US disclosed
US-20050065358-A1 Hafnium-containing material for film formation, method for producing the same, and method for producing hafnium-containing thin film using the same MITSUBISHI MATERIALS CORPORATION (JP) 2005-03-24 US disclosed
EP-1364803-A1 Ink-Jet recording material with improved ozone resistance Felix Schoeller jr Foto- und Spezialpapiere GmbH & Co. KG (DE) 2003-11-26 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050065358-A1 Hafnium-containing material for film formation, method for producing the same, and method for producing hafnium-containing thin film using the same PUF60, HAO2, RTF1 ACE 4432/4885CHRM2 4584/4885ADRA2A 4665/4885
US-20240079595-A1 POSITIVE ELECTRODE MIXTURE, POSITIVE ELECTRODE AND SECONDARY BATTERY MLX, AFF2, PYM1 ACE 4652/4885CHRM2 419/4885ADRA2A 3340/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.