Sugi Predict

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Cyclohexylamine

Cyclohexylamine

SCHEMBL5408527

CC(C)(C)OC(=O)CC(CCCC1CCCCC1)C(=O)O.NC1CCCCC1

nearest known ligand 0.39

Full drug profile on Sugi Atlas →

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ PPARG P37231 3/20 0.38
▸ MEN1 O00255 1/20 0.36
▸ GAA P10253 1/20 0.36
▸ KMT2A Q03164 1/20 0.36
▸ CTSS P25774 1/20 0.35
▸ CTSK P43235 1/20 0.35
▸ BMP1 P13497 5/20 0.35
▸ MMP2 P08253 3/20 0.35
▸ MMP3 P08254 1/20 0.35
▸ SMN1; SMN2 Q16637 1/20 0.34
▸ SLC1A3 P43003 2/20 0.33
▸ SLC1A2 P43004 2/20 0.33
▸ SLC1A1 P43005 2/20 0.33
▸ MMP8 P22894 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Cyclohexylamine SCHEMBL5408520 1.00 PPARG (0.38) PPARGMEN1GAAKMT2ACTSS
SCHEMBL5403076 0.94 PPARG (0.41) PPARGMEN1GAAKMT2ACTSS
SCHEMBL5398181 0.94 PPARG (0.41) PPARGMEN1GAAKMT2ACTSS
SCHEMBL5415572 0.92 PPARG (0.40) PPARGMEN1GAAKMT2ACTSS
SCHEMBL5415566 0.92 PPARG (0.40) PPARGMEN1GAAKMT2ACTSS
SCHEMBL6872894 0.84 BMP1 (0.37) MEN1KMT2ACTSSCTSKBMP1
Cyclohexylamine SCHEMBL5408733 0.82 MMP2 (0.46) PPARGMMP2MMP3
Cyclohexylamine SCHEMBL5408739 0.82 MMP2 (0.46) PPARGMMP2MMP3
SCHEMBL5415569 0.81 SMN1; SMN2 (0.36) PPARGCTSSCTSKBMP1MMP2
SCHEMBL6872622 0.80 SMN1; SMN2 (0.36) MEN1KMT2ACTSSCTSKBMP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1240152-B1 OX(ADI)AZOLYL-HYDROXAMIC ACIDS USEFUL AS PROCOLLAGEN C-PROTEINASE INHIBITORS PFIZER LTD (GB) 2004-12-08 — — EP claimed
US-20030119807-A1 3-Heterocyclylpropanohydroxamic acids BAILEY SIMON (US) 2003-06-26 — — US claimed
JP-2003519133-A — — 2003-06-17 — — JP claimed
EP-1240152-A1 OX(ADI)AZOLYL-HYDROXAMIC ACIDS USEFUL AS PROCOLLAGEN C-PROTEINASE INHIBITORS Pfizer Limited (GB) 2002-09-18 — — EP claimed
WO-2001047901-A1 OX(ADI)AZOLYL-HYDROXAMIC ACIDS USEFUL AS PROCOLLAGEN C-PROTEINASE INHIBITORS PFIZER LIMITED (GB) 2001-07-05 — — WO claimed
US-7214694-B2 3-ox(adi)azolylpropanohydroxamic acids useful as procollagen C-proteinase inhibitors PFIZER INC (US) 2007-05-08 — — US disclosed
EP-1343771-B1 3-OX(ADI)AZOLYLPROPANOHYDROXAMIC ACIDS USEFUL AS PROCOLLAGEN C-PROTEINASE INHIBITORS PFIZER LTD (GB) 2006-04-12 — — EP disclosed
EP-1373231-B1 3-HETEROCYCLYL-PROPANO-HYDROXAMIC ACID AS PCP INHIBITORS PFIZER LTD (GB) 2005-06-08 — — EP disclosed
US-6897306-B2 3-heterocyclylpropanohydroxamic acids PFIZER PRODUCTS, INC. (US) 2005-05-24 — — US disclosed
US-6831088-B2 Wound healing agents; antiscarring agents PFIZER INC. 2004-12-14 — — US disclosed
US-6821972-B2 ANTISCARRING AGENTS; WOUND HEALING AGENTS; ENZYME INHIBITORS PFIZER INC. 2004-11-23 — — US disclosed
US-20040142986-A1 3-ox(adi)azolylpropanohydroxamic acids useful as procollagen C-proteinase inhibitors DATTA USA (GB) 2004-07-22 — — US disclosed
US-20030119807-A1 3-Heterocyclylpropanohydroxamic acids BAILEY SIMON (US) 2003-06-26 — — US disclosed
US-20030069291-A1 3-heterocyclylpropanohydroxamic acid PCP inhibitors PFIZER INC. 2003-04-10 — — US disclosed
US-20020188121-A1 Novel olefination process to itaconate and succinate derivatives DERRICK ANDREW MICHAEL (GB) 2002-12-12 — — US disclosed
US-20020187979-A1 3-heterocyclylpropanohydroxamic acid PCP inhibitors FISH PAUL VINCENT (GB) 2002-12-12 — — US disclosed
US-20020151535-A1 3-ox(adi) azolylpropanohydroxamic acids useful as procollagen C- Proteinase inhibitors PFIZER, INC 2002-10-17 — — US disclosed
US-6452041-B1 REACTING ALDEHYDE OF FORMULA RCHO, OR A PROTECTED DERIVATIVE THEREOF SUCH AS A HEMIACETAL OR ADDUCT THEREOF SUCH AS A BISULPHITE, WITH A PHOSPHORUS COMPOUND TO OBTAIN SUCCINATE OR ITACONATE DERIVATIVE PFIZER INC. 2002-09-17 — — US disclosed
US-6448278-B2 ANTISCARRING AGENT PFIZER INC. 2002-09-10 — — US disclosed
US-20010021718-A1 Procollagen C-proteinase inhibitors PFIZER INC. 2001-09-13 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020188121-A1 Novel olefination process to itaconate and succinate derivatives HOGA1, OGDH, HADHA PPARG 1366/4885MEN1 3498/4885GAA 2588/4885
US-20010021718-A1 Procollagen C-proteinase inhibitors MMP1, CTSL, PREP PPARG 1715/4885MEN1 2045/4885GAA 1264/4885
US-20020187979-A1 3-heterocyclylpropanohydroxamic acid PCP inhibitors MMP1, CPA1, PAH PPARG 1118/4885MEN1 2526/4885GAA 1519/4885
US-20020151535-A1 3-ox(adi) azolylpropanohydroxamic acids useful as procollagen C- Proteinase inhibitors ALPI, TIMP3, MMP1 PPARG 1787/4885MEN1 3336/4885GAA 2132/4885
US-20030119807-A1 3-Heterocyclylpropanohydroxamic acids CPA1, MMP1, PREP PPARG 842/4885MEN1 2545/4885GAA 887/4885
US-20040142986-A1 3-ox(adi)azolylpropanohydroxamic acids useful as procollagen C-proteinase inhibitors ALPI, TIMP3, MMP1 PPARG 1787/4885MEN1 3336/4885GAA 2132/4885
US-20030069291-A1 3-heterocyclylpropanohydroxamic acid PCP inhibitors PAH, CYP2F1, CYP7A1 PPARG 876/4885MEN1 2101/4885GAA 2209/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.