SCHEMBL5419835

SCHEMBL5419835

O=C(O)c1cc(-c2c(Cl)cccc2Cl)ccc1F

nearest known ligand 0.48

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
FABP4 P15090 8/20 0.47
FABP3 P05413 4/20 0.47
FABP5 Q01469 2/20 0.47
TSHR P16473 1/20 0.46
EIF4E P06730 1/20 0.46
ALDH1A1 P00352 1/20 0.44
CNR1 P21554 1/20 0.43
ACLY P53396 1/20 0.43
ACMSD Q8TDX5 1/20 0.43
MRGPRX4 Q96LA9 1/20 0.43
AKR1C2 P52895 1/20 0.42
AKR1C1 Q04828 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5427243 0.87 ALDH1A1 (0.47) FABP4FABP3FABP5EIF4EALDH1A1
SCHEMBL5437372 0.81 GAA (0.50) FABP4FABP3ALDH1A1CNR1ACLY
SCHEMBL31028186 0.77 ACMSD (0.63) ACLYACMSDAKR1C2AKR1C1
SCHEMBL121427 0.77 ACMSD (0.63) ACLYACMSDAKR1C2AKR1C1
SCHEMBL2160051 0.76 DCLRE1B (0.60) ACMSDAKR1C2AKR1C1
SCHEMBL29363677 0.76 DCLRE1B (0.60) ACMSDAKR1C2AKR1C1
SCHEMBL28002285 0.76 FABP4 (0.49) FABP4FABP3FABP5TSHRALDH1A1
SCHEMBL283203 0.74 ALDH1A1 (0.65) TSHRALDH1A1MRGPRX4AKR1C2AKR1C1
SCHEMBL30396748 0.74 ALDH1A1 (0.65) TSHRALDH1A1MRGPRX4AKR1C2AKR1C1
SCHEMBL15580692 0.73 SCN9A (0.47) FABP4FABP5MRGPRX4AKR1C2AKR1C1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070135497-A1 Biphenyl derivative or its salt, and pesticide containing it as an active ingredient ISHIHARA SANGYO KAISHA LTD. (JP) 2007-06-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070135497-A1 Biphenyl derivative or its salt, and pesticide containing it as an active ingredient DDT, HCN1, HCN2 FABP4 2732/4885FABP3 2846/4885FABP5 1771/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.