Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.66 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.59 |
| ▸ | ABCC2 | Q92887 | 1/20 | 0.48 |
| ▸ | KDR | P35968 | 1/20 | 0.46 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.44 |
| ▸ | ERN1 | O75460 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | KRAS | P01116 | 1/20 | 0.40 |
| ▸ | GSK3B | P49841 | 2/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.37 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.37 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.37 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16502064 | 0.86 | ALDH1A1 (0.62) | ALDH1A1KDM4EIMPDH2ABCC2KDR | |
| SCHEMBL30995729 | 0.82 | ALDH1A1 (0.70) | ALDH1A1KDM4EIMPDH2KDRGSK3B | |
| SCHEMBL2275437 | 0.82 | ALDH1A1 (0.70) | ALDH1A1KDM4EIMPDH2KDRGSK3B | |
| SCHEMBL13363658 | 0.79 | ALDH1A1 (0.66) | ALDH1A1KDM4EIMPDH2ABCC2GSK3B | |
| SCHEMBL1092202 | 0.79 | ALDH1A1 (1.00) | ALDH1A1KDM4EIMPDH2KDRPTPN1 | |
| SCHEMBL13108788 | 0.79 | CYP2A6 (0.44) | ALDH1A1KDM4EIMPDH2ABCC2KDR | |
| SCHEMBL1450678 | 0.79 | ALDH1A1 (0.66) | ALDH1A1KDM4EIMPDH2ABCC2 | |
| SCHEMBL1093666 | 0.79 | ALDH1A1 (0.66) | ALDH1A1KDM4EIMPDH2KDRERN1 | |
| SCHEMBL671605 | 0.79 | PDE4B (0.46) | ALDH1A1KDM4EIMPDH2ABCC2CYP2A6 | |
| SCHEMBL22122327 | 0.79 | GAA (0.52) | ALDH1A1KDM4EABCC2CYP2A6ERN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117263933-A | Alpha-carboline derivative and synthesis method thereof | 湘潭大学 | 2023-12-22 | — | — | CN | claimed |
| US-20250177538-A1 | Methods for synthesizing deuterated formylindoles | ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA | 2025-06-05 | — | — | US | disclosed |
| WO-2023250348-A2 | METHODS FOR SYNTHESIZING DEUTERATED FORMYLINDOLES | ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) | 2023-12-28 | — | — | WO | disclosed |
| CN-117263933-A | Alpha-carboline derivative and synthesis method thereof | 湘潭大学 | 2023-12-22 | — | — | CN | disclosed |
| CN-116574048-A | Bromination reaction method of remote indole C-H bond by using sunlight catalysis | 陕西科技大学 | 2023-08-11 | — | — | CN | disclosed |
| CN-116444523-A | Compounds as SMARCA2 inhibitors and uses thereof | 南京圣和药业股份有限公司 | 2023-07-18 | — | — | CN | disclosed |
| CN-112921346-B | Electrochemical synthesis method of 3-formyl indole derivative | 浙江工业大学 | 2022-07-08 | — | — | CN | disclosed |
| CN-109912576-B | Cyclic or spirocyclic diamine pyrimidine-hydroxamic acids and their use | 华东理工大学 | 2021-11-19 | — | — | CN | disclosed |
| CN-112921346-A | Electrochemical synthesis method of 3-formyl indole derivative | 浙江工业大学 | 2021-06-08 | — | — | CN | disclosed |
| US-8507546-B2 | Use of inhibitors of scavenger receptor class proteins for the treatment of infectious diseases | INSTITUTO DE MEDICINA MOLECULAR, FACULDADE DE MEDICINA DA UNIVERSIDADE DE LISBOA (PT) | 2013-08-13 | — | — | US | disclosed |
| WO-2013095305-A1 | BODIPY STRUCTURE FLUORESCENCE PROBES FOR DIVERSE BIOLOGICAL APPLICATIONS | NATIONAL UNIVERSITY OF SINGAPORE (SG) | 2013-06-27 | — | — | WO | disclosed |
| US-20100099676-A1 | SULFONYLUREA DERIVATIVE CAPABLE OF SELECTIVELY INHIBITING MMP-13 | SHIONOGI & CO., LTD. (JP) | 2010-04-22 | — | — | US | disclosed |
| US-20100099676-A1 | SULFONYLUREA DERIVATIVE CAPABLE OF SELECTIVELY INHIBITING MMP-13 | SHIONOGI & CO., LTD. (JP) | 2010-04-22 | — | — | US | disclosed |
| EP-2128134-A1 | SULFONYLUREA DERIVATIVE CAPABLE OF SELECTIVELY INHIBITING MMP-13 | Shionogi&Co., Ltd. (JP) | 2009-12-02 | — | — | EP | disclosed |
| US-20090105162-A1 | SUBSTITUTED FUSED HETEROCYCLIC C-GLYCOSIDES | RYBCZYNSKI PHILIP | 2009-04-23 | — | — | US | disclosed |
| US-7482330-B2 | Substituted fused heterocyclic C-glycosides | JANSSEN PHARMACEUTICA N.V. (BE) | 2009-01-27 | — | — | US | disclosed |
| US-20070185079-A1 | Therapeutic agents I | ASTRAZENECA AB (SE) | 2007-08-09 | — | — | US | disclosed |
| US-7202265-B2 | Indolinone combinatorial libraries and related products and methods for the treatment of disease | SUGEN, INC. (US) | 2007-04-10 | — | — | US | disclosed |
| US-7202265-B2 | Indolinone combinatorial libraries and related products and methods for the treatment of disease | SUGEN, INC. (US) | 2007-04-10 | — | — | US | disclosed |
| CN-1906169-A | Therapeutic agents I | ASTRAZENECA AB (SE) | 2007-01-31 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250177538-A1 | Methods for synthesizing deuterated formylindoles | TDO2, CISD2, ALAD | ALDH1A1 2258/4885KDM4E 2663/4885IMPDH2 1051/4885 |
| US-20100099676-A1 | SULFONYLUREA DERIVATIVE CAPABLE OF SELECTIVELY INHIBITING MMP-13 | MMP13, MMP3, MMP26 | ALDH1A1 469/4885KDM4E 1419/4885IMPDH2 2449/4885 |
| US-20070185079-A1 | Therapeutic agents I | HTT, GRIN2A, GRIN1 | ALDH1A1 1661/4885KDM4E 2659/4885IMPDH2 4318/4885 |
| US-20090105162-A1 | SUBSTITUTED FUSED HETEROCYCLIC C-GLYCOSIDES | UGCG, UGGT1, GCG | ALDH1A1 3466/4885KDM4E 3904/4885IMPDH2 3750/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.