SCHEMBL544934

SCHEMBL544934

CN1C(=O)N(C)C(Cl)(Cl)C1=O

nearest known ligand 0.35

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.35
MAPT P10636 2/20 0.35
LMNA P02545 2/20 0.35
KDM4E B2RXH2 1/20 0.35
HPGD P15428 1/20 0.35
HTT P42858 1/20 0.35
CACNA1B Q00975 1/20 0.35
APBA1 Q02410 1/20 0.35
MAPK1 P28482 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
HSD17B10 Q99714 1/20 0.32
KDM4C Q9H3R0 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.30
AKR1B1 P15121 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8582236 0.87 KDM4E (0.33) ALDH1A1MAPTLMNAKDM4EHPGD
SCHEMBL8185561 0.87 KDM4E (0.33) ALDH1A1MAPTLMNAKDM4EHPGD
SCHEMBL9539449 0.81
SCHEMBL210683 0.75 KDM4E (0.33) ALDH1A1MAPTLMNAKDM4EHPGD
SCHEMBL3252049 0.72 F2 (0.33) ALDH1A1MAPTLMNAKDM4EHPGD
SCHEMBL417571 0.70 PLA2G7 (0.39) LMNAHSD17B10
SCHEMBL11423007 0.70 KDM4E (0.31) ALDH1A1LMNAKDM4EHPGDSMN1; SMN2
SCHEMBL1001742 0.69 KDM4E (0.30) ALDH1A1MAPTLMNAKDM4EHPGD
SCHEMBL11391543 0.68 KMT2A (0.33) ALDH1A1SMN1; SMN2HSD17B10L3MBTL1
SCHEMBL1363456 0.67 LMNA (0.34) LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1664 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4688024-A1 CATHETERS ConvaTec Limited (GB) 2026-02-11 EP claimed
US-20260027268-A1 CATHETERS CONVATEC LTD (GB) 2026-01-29 US claimed
US-12480149-B2 Method for the rapid detection of bacterial spores in an industrial process ECOLAB USA INC. (US) 2025-11-25 US claimed
EP-4648810-A1 CATHETERS ConvaTec Limited (GB) 2025-11-19 EP claimed
US-20250339642-A1 CATHETERS CONVATEC LTD (GB) 2025-11-06 US claimed
US-12329151-B2 Ion enhancement KING TECHNOLOGY, INC. (US) 2025-06-17 US claimed
CN-115335153-B Formulation delivery system with solid chemical components W·M·巴尔公司 2025-06-10 CN claimed
EP-3652330-B1 A RAPID APPROACH FOR DETECTION OF BACTERIAL SPORES ECOLAB USA INC (US) 2025-04-30 EP claimed
US-20250011297-A1 PROCESS AND INTERMEDIATES FOR PREPARATION OF ISOFETAMID ADAMA MAKHTESHIM LTD. (IL) 2025-01-09 US claimed
CN-119212980-A Preparation method of pyridine nitroxide compound 上海济煜医药科技有限公司 2024-12-27 CN claimed
EP-0293400-A1 METHOD FOR CONTROLLING PLANT DISEASES AND MICROORGANISMS IN THE PRESENCE OF PLANTS GREAT LAKES CHEMICAL CORPORATION (US) 1988-12-07 EP claimed
CN-88100379-A Handle the method on stratum 1988-11-02 CN claimed
WO-1988002987-A1 METHOD FOR CONTROLLING PLANT DISEASES AND MICROORGANISMS IN THE PRESENCE OF PLANTS GREAT LAKES CHEMICAL CORPORATION (US) 1988-05-05 WO claimed
US-4713079-A SPHERES; BUFFERS, BINDERS, CONTROLLED PH, INORGANIC FILLERS; LOW DAMAGE TO FABRICS, ELIMINATES PINHOLING LEVER BROTHERS COMPANY (US) 1987-12-15 US claimed
EP-0228105-A2 Particles containing dihalohydantoin bleach in a diluted core UNILEVER N.V. (NL) 1987-07-08 EP claimed
US-4657285-A Tubular rubber products BRIDGESTONE CORPORATION (JP) 1987-04-14 US claimed
EP-0206725-A2 Lavatory cleansing compositions JEYES GROUP LIMITED (GB) 1986-12-30 EP claimed
US-4621096-A CALCIUM CHLORIDE, WATER, STRENGTH GREAT LAKES CHEMICAL CORPORATION (US) 1986-11-04 US claimed
US-4532330-A Halogenating dimethylhydantoin in presence of water and source of calcium and hydroxide ions, repeating, separating dihalogenated product containing calcium chloride and water without washing GREAT LAKES CHEMICAL CORPORATION (US) 1985-07-30 US claimed
US-4120650-A Laundering process for dual bleaching stained fabrics BASF WYANDOTTE CORPORATION (US) 1978-10-17 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250011297-A1 PROCESS AND INTERMEDIATES FOR PREPARATION OF ISOFETAMID IDH2, FH, SDHA ALDH1A1 871/4885MAPT 1234/4885LMNA 4129/4885
US-20260027268-A1 CATHETERS NACA, CD63, SLC6A6 ALDH1A1 3508/4885MAPT 685/4885LMNA 3297/4885
US-12329151-B2 Ion enhancement HCN2, HCN1, SLC18A1 ALDH1A1 1969/4885MAPT 4500/4885LMNA 4074/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.