Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMPRSS2 | O15393 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | NPC1 | O15118 | 5/20 | 0.54 |
| ▸ | RAB9A | P51151 | 5/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | CASP3 | P42574 | 1/20 | 0.54 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.54 |
| ▸ | KCNA1 | Q09470 | 2/20 | 0.52 |
| ▸ | KCNAB1 | Q14722 | 2/20 | 0.52 |
| ▸ | NAMPT | P43490 | 1/20 | 0.49 |
| ▸ | ESR1 | P03372 | 1/20 | 0.48 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | THRB | P10828 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3402909 | 0.91 | NPC1 (0.67) | TMPRSS2KMT2ANPC1RAB9APOLB | |
| SCHEMBL5467142 | 0.86 | ESR2 (0.58) | TMPRSS2KMT2ANPC1RAB9APOLB | |
| SCHEMBL5458367 | 0.84 | RAB9A (0.69) | KMT2ANPC1RAB9APOLBCASP3 | |
| SCHEMBL3404203 | 0.83 | THRB (0.49) | TMPRSS2KMT2ANPC1RAB9APOLB | |
| SCHEMBL3405294 | 0.83 | RAB9A (0.63) | TMPRSS2KMT2ANPC1RAB9ACASP3 | |
| SCHEMBL5469377 | 0.81 | POLB (0.55) | TMPRSS2KMT2ANPC1RAB9APOLB | |
| SCHEMBL10004669 | 0.81 | THRB (0.45) | TMPRSS2KMT2ANPC1RAB9APOLB | |
| SCHEMBL10004662 | 0.81 | THRB (0.45) | TMPRSS2KMT2ANPC1RAB9APOLB | |
| SCHEMBL5460595 | 0.81 | CASP3 (0.70) | TMPRSS2KMT2ANPC1RAB9ACASP3 | |
| SCHEMBL11295872 | 0.80 | ESR1 (0.71) | TMPRSS2KMT2ANPC1RAB9AESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070249620-A1 | Urea Derivative | SANKYO COMPANY, LIMITED (JP) | 2007-10-25 | — | — | US | disclosed |
| EP-1764360-A1 | UREA DERIVATIVE | Sankyo Company, Limited (JP) | 2007-03-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070249620-A1 | Urea Derivative | UGP2, SLC14A1, DGAT1 | TMPRSS2 3127/4885KMT2A 1350/4885NPC1 1089/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.