SCHEMBL546314

SCHEMBL546314

COC(=O)C(F)(F)S(=O)(=O)O

nearest known ligand 0.50

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.50
L3MBTL1 Q9Y468 2/20 0.50
DGAT1 O75907 1/20 0.34
F2 P00734 1/20 0.34
PRSS1 P07477 1/20 0.34
PRSS2 P07478 1/20 0.34
PRSS3 P35030 1/20 0.34
GAA P10253 1/20 0.33
PTPRB P23467 2/20 0.33
KCNN4 O15554 1/20 0.31
PTPN2 P17706 1/20 0.30
PTPN1 P18031 1/20 0.30
PTPRA P18433 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4849380 0.98 ALDH1A1 (0.48) ALDH1A1L3MBTL1DGAT1F2PRSS1
Adamantane SCHEMBL547077 0.88 ALDH1A1 (0.40) ALDH1A1L3MBTL1
SCHEMBL15491315 0.80 DGAT1 (0.34) ALDH1A1L3MBTL1DGAT1F2PRSS1
SCHEMBL95855 0.80 DGAT1 (0.34) ALDH1A1L3MBTL1DGAT1F2PRSS1
SCHEMBL12135439 0.79 ALDH1A1 (0.36) ALDH1A1L3MBTL1
SCHEMBL18211282 0.78 DGAT1 (0.38) ALDH1A1L3MBTL1DGAT1F2PRSS1
SCHEMBL12211903 0.78 CA1 (0.39) ALDH1A1L3MBTL1DGAT1F2PRSS1
SCHEMBL28344966 0.78 ALDH1A1 (0.33) ALDH1A1L3MBTL1DGAT1F2PRSS1
SCHEMBL18068152 0.78 ALDH1A1 (0.33) ALDH1A1L3MBTL1DGAT1F2PRSS1
SCHEMBL15800908 0.78 ALDH1A1 (0.33) ALDH1A1L3MBTL1DGAT1F2PRSS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 732 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260138956-A1 NOVEL COMPOUNDS AND USES THEREOF RECURSION PHARMACEUTICALS INC (US) 2026-05-21 US disclosed
US-20260124222-A1 ISOTHIAZOLYLCARBOXAMIDE COMPOUNDS AND THEIR USE IN THERAPY HOTSPOT THERAPEUTICS INC (US) 2026-05-07 US disclosed
US-12617782-B2 Pyridazinones as PARP7 inhibitors RIBON THERAPEUTICS, INC. (US) 2026-05-05 US disclosed
US-12612412-B2 Antiviral heterocyclic compounds ENANTA PHARMACEUTICALS, INC. (US) 2026-04-28 US disclosed
US-12606541-B2 PPARg modulators and methods of use EISAI R&D MANAGEMENT CO., LTD. (JP) 2026-04-21 US disclosed
EP-4709374-A2 KCC2 POTENTIATORS AND USES THEREOF Axonis Therapeutics, Inc. (US) 2026-03-18 EP disclosed
US-20260062402-A1 KCC2 POTENTIATORS AND USES THEREOF AXONIS THERAPEUTICS INC (US) 2026-03-05 US disclosed
CN-121574131-A Heterocyclic compounds for insect repellent 勃林格殷格翰动物保健有限公司 2026-02-27 CN disclosed
EP-4688754-A1 KCC2 POTENTIATORS AND USES THEREOF Axonis Therapeutics, Inc. (US) 2026-02-11 EP disclosed
US-20260028351-A1 KCC2 POTENTIATORS AND USES THEREOF AXONIS THERAPEUTICS, INC. 2026-01-29 US disclosed
US-20080026331-A1 Lactone-containing compound, polymer, resist composition, and patterning process SHIN-ETSU CHEMICAL CO., LTD. 2008-01-31 US disclosed
US-20080008962-A1 Polymerizable ester compounds, polymers, resist compositions and patterning process SHIN-ETSU CHEMICAL CO., LTD. 2008-01-10 US disclosed
US-20080008965-A1 Ester compounds and their preparation, polymers, resist compositions and patterning process SHIN-ETSU CHEMICAL CO., LTD. 2008-01-10 US disclosed
US-20070298352-A1 NOVEL SULFONATE SALTS AND DERIVATIVES, PHOTOACID GENERATORS, RESIST COMPOSITIONS, AND PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2007-12-27 US disclosed
US-7189492-B2 Photosensitive composition and pattern forming method using the same FUJI PHOTO FILM CO., LTD. (JP) 2007-03-13 US disclosed
CN-1916760-A Acid generator, sulfonic acid derivative and radiation-sensitive resin composition JSR CORP (JP) 2007-02-21 CN disclosed
US-20070003871-A1 Positive photosensitive composition FUJI PHOTO FILM CO., LTD. 2007-01-04 US disclosed
US-20070003871-A1 Positive photosensitive composition FUJI PHOTO FILM CO., LTD. 2007-01-04 US disclosed
CN-1276303-C Acid generator and radiation-sensitive resin composition JSR CORP (JP) 2006-09-20 CN disclosed
CN-1432873-A Acid generator, sulfonic acid derivative and radiation-sensitive resin composition JSR CORP (JP) 2003-07-30 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260138956-A1 NOVEL COMPOUNDS AND USES THEREOF SLC10A1, NR3C2, CYP2C8 ALDH1A1 230/4885L3MBTL1 3399/4885DGAT1 1276/4885
US-20260028351-A1 KCC2 POTENTIATORS AND USES THEREOF GRIN2C, HCN1, KCNC1 ALDH1A1 3779/4885L3MBTL1 3008/4885DGAT1 2475/4885
US-20070298352-A1 NOVEL SULFONATE SALTS AND DERIVATIVES, PHOTOACID GENERATORS, RESIST COMPOSITIONS, AND PATTERNING PROCESS HCN3, ASIC3, TST ALDH1A1 2781/4885L3MBTL1 4521/4885DGAT1 1654/4885
US-20080008965-A1 Ester compounds and their preparation, polymers, resist compositions and patterning process ESR1, H1-2, H1-4 ALDH1A1 1418/4885L3MBTL1 2403/4885DGAT1 1054/4885
US-12617782-B2 Pyridazinones as PARP7 inhibitors PARP3, PARP2, PARP1 ALDH1A1 686/4885L3MBTL1 1924/4885DGAT1 3938/4885
US-12612412-B2 Antiviral heterocyclic compounds ZC3HAV1, NHERF1, HM13 ALDH1A1 4093/4885L3MBTL1 2620/4885DGAT1 4834/4885
US-12606541-B2 PPARg modulators and methods of use PPARG, PPARA, PPARD ALDH1A1 1374/4885L3MBTL1 4535/4885DGAT1 716/4885
US-20260062402-A1 KCC2 POTENTIATORS AND USES THEREOF HCN2, HCN1, HCN4 ALDH1A1 2748/4885L3MBTL1 3146/4885DGAT1 3070/4885
US-20260124222-A1 ISOTHIAZOLYLCARBOXAMIDE COMPOUNDS AND THEIR USE IN THERAPY MALT1, BCL6, BCL6B ALDH1A1 1842/4885L3MBTL1 1165/4885DGAT1 751/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.