SCHEMBL546491

SCHEMBL546491

CCC(=C(C)C(=O)O)C12CC3CC(CC(C3)C1)C2

nearest known ligand 0.46

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
HSD11B1 P28845 2/20 0.40
GLA P06280 1/20 0.40
ALDH1A1 P00352 6/20 0.39
TSHR P16473 2/20 0.39
LMNA P02545 1/20 0.39
HTT P42858 2/20 0.39
KDM4E B2RXH2 1/20 0.39
MAPT P10636 2/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
CNR2 P34972 1/20 0.37
POLB P06746 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL595456 1.00 HSD11B1 (0.40) HSD11B1GLAALDH1A1TSHRLMNA
SCHEMBL3207184 0.85 HSD11B1 (0.40) HSD11B1GLAALDH1A1TSHRLMNA
SCHEMBL3207190 0.85 HSD11B1 (0.40) HSD11B1GLAALDH1A1TSHRLMNA
SCHEMBL28179101 0.78 LMNA (0.38) HSD11B1GLAALDH1A1TSHRLMNA
SCHEMBL524018 0.76 GLA (0.44) HSD11B1GLAALDH1A1HTTKDM4E
SCHEMBL524017 0.76 GLA (0.44) HSD11B1GLAALDH1A1HTTKDM4E
SCHEMBL906383 0.76 GLA (0.44) HSD11B1GLAALDH1A1HTTKDM4E
SCHEMBL2026422 0.76 GLA (0.44) HSD11B1GLAALDH1A1HTTKDM4E
SCHEMBL1218819 0.76 GLA (0.44) HSD11B1GLAALDH1A1LMNAHTT
SCHEMBL7521812 0.76 HSD11B1 (0.36) HSD11B1GLAALDH1A1TSHRLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8557501-B2 Developable bottom antireflective coating compositions especially suitable for ion implant applications INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2013-10-15 US claimed
US-20120178029-A1 DEVELOPABLE BOTTOM ANTIREFLECTIVE COATING COMPOSITIONS ESPECIALLY SUITABLE FOR ION IMPLANT APPLICATIONS INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2012-07-12 US claimed
US-8182978-B2 Developable bottom antireflective coating compositions especially suitable for ion implant applications INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2012-05-22 US claimed
US-20090181171-A1 Method of Controlling Orientation of Domains in Block Copolymer Films INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2009-07-16 US claimed
US-20240055382-A1 METALLIZATION METHOD U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT 2024-02-15 US disclosed
US-20230420401-A1 METALLIZATION METHOD U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT 2023-12-28 US disclosed
US-20160130462-A1 TOPCOAT COMPOSITIONS AND PHOTOLITHOGRAPHIC METHODS ROHM & HAAS ELECT MAT (US) 2016-05-12 US disclosed
US-20150195916-A1 FORMATION OF A COMPOSITE PATTERN INCLUDING A PERIODIC PATTERN SELF-ALIGNED TO A PREPATTERN INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2015-07-09 US disclosed
US-8557501-B2 Developable bottom antireflective coating compositions especially suitable for ion implant applications INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2013-10-15 US disclosed
US-8540925-B2 Photocurable composition, micropattern-formed product and its production process ASAHI GLASS COMPANY, LIMITED (JP) 2013-09-24 US disclosed
US-8491965-B2 Method of controlling orientation of domains in block copolymer films INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2013-07-23 US disclosed
US-20120178029-A1 DEVELOPABLE BOTTOM ANTIREFLECTIVE COATING COMPOSITIONS ESPECIALLY SUITABLE FOR ION IMPLANT APPLICATIONS INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2012-07-12 US disclosed
WO-2009019574-A1 PHOTORESIST COMPOSITION FOR DEEP UV AND PROCESS THEREOF AZ ELECTRONIC MATERIALS USA CORP. (DE) 2009-02-12 WO disclosed
US-20090042148-A1 Photoresist Composition for Deep UV and Process Thereof AZ ELECTRONIC MATERIALS USA CORP. 2009-02-12 US disclosed
US-20080107870-A1 PHOTOCURABLE COMPOSITION, MICROPATTERN-FORMED PRODUCT AND ITS PRODUCTION PROCESS ASAHI GLASS CO., LTD. (JP) 2008-05-08 US disclosed
US-20080003517-A1 Fluorine-Containing Cyclic Compound, Fluorine-Containing Polymer Compound, Resist Material Using Same and Method for Forming Pattern CENTRAL GLASS COMPANY, LIMITED (JP) 2008-01-03 US disclosed
US-6908722-B2 Acid generator, sulfonic acid, sulfonic acid derivatives and radiation-sensitive resin composition JSR CORPORATION (JP) 2005-06-21 US disclosed
US-20030113658-A1 Acid generator, sulfonic acid, sulfonic acid derivatives and radiation-sensitive resin composition JSR CORPORATION (JP) 2003-06-19 US disclosed
EP-1270553-A2 Acid generator, sulfonic acid, sulfonic acid derivatives and radiation-sensitive resin composition JSR Corporation (JP) 2003-01-02 EP disclosed
WO-2002021212-A2 FLUORINATED PHENOLIC POLYMERS AND PHOTORESIST COMPOSITIONS COMPRISING SAME SHIPLEY COMPANY, L.L.C. (US) 2002-03-14 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080003517-A1 Fluorine-Containing Cyclic Compound, Fluorine-Containing Polymer Compound, Resist Material Using Same and Method for Forming Pattern AFF1, AFF2, FGFR1 HSD11B1 2242/4885GLA 4244/4885ALDH1A1 903/4885
US-20030113658-A1 Acid generator, sulfonic acid, sulfonic acid derivatives and radiation-sensitive resin composition ASIC1, PFAS, RARA HSD11B1 3894/4885GLA 816/4885ALDH1A1 1216/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.