SCHEMBL5476629

SCHEMBL5476629

COc1cc(C=O)cc(C)c1O

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ EGFR P00533 1/20 0.58
▸ ALDH1A1 P00352 3/20 0.55
▸ HPGD P15428 2/20 0.55
▸ TRIM24 O15164 1/20 0.55
▸ ALDH5A1 P51649 1/20 0.55
▸ ABAT P80404 1/20 0.55
▸ TDP1 Q9NUW8 1/20 0.55
▸ TRIM33 Q9UPN9 1/20 0.55
▸ ERN1 O75460 5/20 0.53
▸ PTGS1 P23219 4/20 0.51
▸ PTGS2 P35354 4/20 0.51
▸ ALOX5 P09917 3/20 0.51
▸ TSHR P16473 1/20 0.50
▸ AOX1 Q06278 1/20 0.50
▸ CYP3A4 P08684 2/20 0.49
▸ CYP2B6 P20813 2/20 0.49
▸ CYP1A2 P05177 1/20 0.49
▸ CYP2D6 P10635 1/20 0.49
▸ CYP2C9 P11712 1/20 0.49
▸ MAPT P10636 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29952164 1.00 EGFR (0.58) EGFRALDH1A1HPGDTRIM24ALDH5A1
Syringaldehyde SCHEMBL150376 0.88 ALDH1A1 (0.62) ALDH1A1HPGDTRIM24ALDH5A1ABAT
Syringaldehyde SCHEMBL30119623 0.88 ALDH1A1 (0.62) ALDH1A1HPGDTRIM24ALDH5A1ABAT
Syringaldehyde SCHEMBL2110596 0.88 ALDH1A1 (0.62) ALDH1A1HPGDTRIM24ALDH5A1ABAT
Syringaldehyde SCHEMBL11013780 0.86 ALDH1A1 (0.60) ALDH1A1HPGDTRIM24ALDH5A1ABAT
Syringaldehyde SCHEMBL28299840 0.86 ALDH1A1 (0.60) ALDH1A1HPGDTRIM24ALDH5A1ABAT
Syringaldehyde SCHEMBL27352107 0.86 ALDH1A1 (0.60) ALDH1A1HPGDTRIM24ALDH5A1ABAT
Syringaldehyde SCHEMBL29724072 0.86 ALDH1A1 (0.60) ALDH1A1HPGDTRIM24ALDH5A1ABAT
Syringaldehyde SCHEMBL28642631 0.86 ALDH1A1 (0.60) ALDH1A1HPGDTRIM24ALDH5A1ABAT
SCHEMBL28901029 0.85 ERN1 (0.69) EGFRALDH1A1HPGDTRIM24ALDH5A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 120 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112079697-A Preparation method of 5-methyl vanillin 上海应用技术大学 2020-12-15 — — CN claimed
CN-111707754-A Method for measuring guaiacol, ortho-vanillin, 5-methyl vanillin and 5-aldehyde vanillin in vanillin 上海应用技术大学 2020-09-25 — — CN claimed
CN-104203891-B Process for producing alkoxy-hydroxybenzaldehydes substantially free of alkyl-alkoxy-hydroxybenzaldehydes 罗地亚运作公司 2019-03-15 — — CN claimed
EP-2760815-B1 METHOD FOR PRODUCING ALKOXY-HYDROXYBENZALDEHYDE THAT IS SUBSTANTIALLY FREE OF ALKYL-ALKOXY-HYDROXYBENZALDEHYDE RHODIA OPERATIONS (FR) 2016-08-24 — — EP claimed
US-9284247-B2 Method for producing alkoxy-hydroxybenzaldehyde that is substantially free of alkyl-alkoxy-hydroxybenzaldehyde RHODIA OPERATIONS (FR) 2016-03-15 — — US claimed
US-20150203428-A1 Method for producing alkoxy-hydroxybenzaldehyde that is substantially free of alkyl-alkoxy-hydroxybenzaldehyde SPECIALTY OPERATIONS FRANCE (FR) 2015-07-23 — — US claimed
EP-2760815-A1 METHOD FOR PRODUCING ALKOXY-HYDROXYBENZALDEHYDE THAT IS SUBSTANTIALLY FREE OF ALKYL-ALKOXY-HYDROXYBENZALDEHYDE RHODIA OPERATIONS (FR) 2014-08-06 — — EP claimed
WO-2014016145-A1 METHOD FOR PRODUCING ALKOXY-HYDROXYBENZALDEHYDE THAT IS SUBSTANTIALLY FREE OF ALKYL-ALKOXY-HYDROXYBENZALDEHYDE RHODIA OPERATIONS (FR) 2014-01-30 — — WO claimed
WO-2024135708-A1 METHOD FOR PRODUCING COMPOUND, POLYMER, COMPOSITION, AND PATTERN FORMATION METHOD 三菱瓦斯化学株式会社 2024-06-27 — — WO disclosed
US-11814597-B2 Process for the production of oxidized wood products ORGANOFUEL SWEDEN AB (SE) 2023-11-14 — — US disclosed
US-11654198-B2 Application of combination of polyethylene glycol and local anesthetic in non-narcotic analgesia JENKEM TECHNOLOGY CO., LTD. (TIANJIN) (CN) 2023-05-23 — — US disclosed
US-11654198-B2 Application of combination of polyethylene glycol and local anesthetic in non-narcotic analgesia JENKEM TECHNOLOGY CO., LTD. (TIANJIN) (CN) 2023-05-23 — — US disclosed
US-11584727-B2 2-thioxothiazolidin-4-one derivatives active as transthyretin ligands and uses thereof BSIM THERAPEUTICS, S.A. (PT) 2023-02-21 — — US disclosed
US-11584727-B2 2-thioxothiazolidin-4-one derivatives active as transthyretin ligands and uses thereof BSIM THERAPEUTICS, S.A. (PT) 2023-02-21 — — US disclosed
WO-1997002037-A1 COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM SYMPHAR S.A. (CH) 1997-01-23 — — WO disclosed
EP-0334119-B1 COMPOUNDS FOR INHIBITING THE BIOSYNTHESIS OF LIPOXYGENASE-DERIVED METABOLITES OF ARACHIDONIC ACID BOEHRINGER INGELHEIM PHARMACEUTICALS INC. (US) 1993-06-16 — — EP disclosed
EP-0334119-A1 Compounds for inhibiting the biosynthesis of lipoxygenase-derived metabolites of arachidonic acid BOEHRINGER INGELHEIM PHARMACEUTICALS INC. (US) 1989-09-27 — — EP disclosed
US-4157286-A Production of 1,2-bis(hydroxyphenyl)ethane-1,2-diols by electrolytic reduction MONSANTO COMPANY (US) 1979-06-05 — — US disclosed
US-4133729-A Production of 1,2-bis(hydroxy-phenyl)ethane-1,2-diols by electrolytic reduction MONSANTO COMPANY (US) 1979-01-09 — — US disclosed
US-4087336-A Electrolytic reductive coupling of hydroxybenzaldehydes MONSANTO COMPANY (US) 1978-05-02 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11814597-B2 Process for the production of oxidized wood products NOX4, NOX5, AOC2 EGFR 4579/4885ALDH1A1 73/4885HPGD 106/4885
US-20150203428-A1 Method for producing alkoxy-hydroxybenzaldehyde that is substantially free of alkyl-alkoxy-hydroxybenzaldehyde HPD, APEH, HMBS EGFR 3986/4885ALDH1A1 29/4885HPGD 227/4885
US-11584727-B2 2-thioxothiazolidin-4-one derivatives active as transthyretin ligands and uses thereof TTR, TTPA, MTPN EGFR 4120/4885ALDH1A1 2165/4885HPGD 3647/4885
US-11654198-B2 Application of combination of polyethylene glycol and local anesthetic in non-narcotic analgesia OPRL1, OPRK1, OPRM1 EGFR 999/4885ALDH1A1 689/4885HPGD 558/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback