SCHEMBL5507220

SCHEMBL5507220

SSC(c1ccccc1)(c1ccccc1)c1ccccc1

nearest known ligand 0.44

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 12/20 0.44
TSHR P16473 3/20 0.41
KCNN4 O15554 3/20 0.41
ALDH1A1 P00352 1/20 0.41
MAPK1 P28482 1/20 0.36
LMNA P02545 1/20 0.33
ALOX12 P18054 1/20 0.33
ACHE P22303 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL34009 0.75 KIF11 (0.48) KIF11TSHRKCNN4ALDH1A1MAPK1
SCHEMBL7715769 0.75 KIF11 (0.48) KIF11TSHRKCNN4ALDH1A1MAPK1
SCHEMBL580603 0.74 KIF11 (0.43) KIF11TSHRKCNN4ALDH1A1MAPK1
SCHEMBL7611624 0.72 KCNN4 (0.38) KIF11TSHRKCNN4ALDH1A1MAPK1
SCHEMBL775521 0.72 MAPK1 (0.44) TSHRKCNN4ALDH1A1MAPK1LMNA
SCHEMBL23561105 0.71 KCNN4 (0.48) KIF11TSHRKCNN4ALDH1A1MAPK1
SCHEMBL114237 0.71 KIF11 (0.50) KIF11TSHRKCNN4ALDH1A1MAPK1
SCHEMBL4458431 0.71 KIF11 (0.44) KIF11TSHRKCNN4ALDH1A1MAPK1
SCHEMBL84106 0.71 KIF11 (0.44) KIF11TSHRKCNN4ALDH1A1MAPK1
SCHEMBL4976416 0.71 KIF11 (0.44) KIF11TSHRKCNN4ALDH1A1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240254149-A1 Chemical Phosphorylation Reagents, Preparation, and Their Uses OLIX US, INC. 2024-08-01 US disclosed
EP-4341270-A1 CHEMICAL PHOSPHORYLATION REAGENTS, PREPARATION, AND THEIR USES Olix US, Inc. (US) 2024-03-27 EP disclosed
CN-117580848-A Chemical phosphorylating reagent, preparation and use thereof 奥利克斯美国公司 2024-02-20 CN disclosed
CN-109666121-B Hybrid dynamic cross-linked polymer and application thereof 厦门逍扬运动科技有限公司 2023-09-22 CN disclosed
WO-2022246196-A1 CHEMICAL PHOSPHORYLATION REAGENTS, PREPARATION, AND THEIR USES OLIX US, INC. (US) 2022-11-24 WO disclosed
US-20210163685-A1 PHOTOSENSITIZER FOR A PHOTOCATHODE CFSO GMBH (DE) 2021-06-03 US disclosed
US-20070004700-A1 2-Thioethenyl substituted carbapenem derivatives MEIJI SEIKA KAISHA, LTD. (JP) 2007-01-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210163685-A1 PHOTOSENSITIZER FOR A PHOTOCATHODE PPOX, CRYAA, ACP1 KIF11 4028/4885TSHR 2341/4885KCNN4 1221/4885
US-20070004700-A1 2-Thioethenyl substituted carbapenem derivatives MTAP, BLVRB, BPGM KIF11 4452/4885TSHR 1341/4885KCNN4 4457/4885
US-20240254149-A1 Chemical Phosphorylation Reagents, Preparation, and Their Uses PTMS, PPP4C, CHAMP1 KIF11 1762/4885TSHR 1921/4885KCNN4 4066/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.