SCHEMBL5509475

SCHEMBL5509475

CCc1cc(Cc2cc(CC)c(NCl)c(CC)c2)cc(CC)c1NCl

nearest known ligand 0.33

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
SHBG P04278 1/20 0.32
DHFR P00374 2/20 0.32
ALDH1A1 P00352 1/20 0.30
LMNA P02545 1/20 0.30
MAPT P10636 1/20 0.30
HPGD P15428 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2782428 0.87 HSPA5 (0.39)
SCHEMBL9861529 0.81 SHBG (0.34) SHBGDHFRLMNAHPGD
SCHEMBL28756419 0.78 RAPGEF4 (0.36) SHBGALDH1A1LMNAHPGD
SCHEMBL727390 0.74 ELANE (0.35) SHBGDHFR
SCHEMBL14509458 0.72 SHBG (0.33) SHBGDHFR
SCHEMBL7189588 0.71 GABRA1 (0.48) ALDH1A1
SCHEMBL727589 0.71 ALDH1A1 (0.44) ALDH1A1
SCHEMBL12284735 0.70 GAA (0.50) ALDH1A1LMNAMAPTHPGD
SCHEMBL25314219 0.69 HTT (0.42) ALDH1A1LMNAMAPTHPGD
SCHEMBL4364941 0.69 DHFR (0.53) SHBGDHFR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1406890-A4 PHTHALIDE COMPOUNDS USEFUL IN OPTICAL RECORDING TRUSTEES BOSTON COLLEGE (US) 2004-11-24 EP claimed
EP-1406890-A2 PHTHALIDE COMPOUNDS USEFUL IN OPTICAL RECORDING Trustees of Boston College (US) 2004-04-14 EP claimed
US-6548608-B2 Thermoplastic resin; polyetherimide copolymer, polysulfones and epoxy resin INSTITUT FRANCAIS DU PETROLE (FR) 2003-04-15 US claimed
US-20030027063-A1 Apparatus and materials for three-dimensional optical data storage and retrieval THE TRUSTEES OF BOSTON COLLEGE 2003-02-06 US claimed
WO-2003006450-A2 PHTHALIDE COMPOUNDS USEFUL IN OPTICAL RECORDING TRUSTEES OF BOSTOON COLLEGE (US) 2003-01-23 WO claimed
US-7282320-B2 Apparatus for three-dimensional optical data storage and retrieval THE TRUSTEES OF BOSTON COLLEGE (US) 2007-10-16 US disclosed
US-20060057497-A1 Apparatus for three-dimensional optical data storage and retrieval THE TRUSTEES OF BOSTON COLLEGE 2006-03-16 US disclosed
US-6998214-B2 Methods for three-dimensional optical data storage and retrieval THE TRUSTEES OF BOSTON COLLEGE (US) 2006-02-14 US disclosed
EP-1406890-A4 PHTHALIDE COMPOUNDS USEFUL IN OPTICAL RECORDING TRUSTEES BOSTON COLLEGE (US) 2004-11-24 EP disclosed
EP-1406890-A2 PHTHALIDE COMPOUNDS USEFUL IN OPTICAL RECORDING Trustees of Boston College (US) 2004-04-14 EP disclosed
US-20030027063-A1 Apparatus and materials for three-dimensional optical data storage and retrieval THE TRUSTEES OF BOSTON COLLEGE 2003-02-06 US disclosed
WO-2003006450-A2 PHTHALIDE COMPOUNDS USEFUL IN OPTICAL RECORDING TRUSTEES OF BOSTOON COLLEGE (US) 2003-01-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060057497-A1 Apparatus for three-dimensional optical data storage and retrieval EIF2B3, RPL13, WDR3 SHBG 4734/4885DHFR 4779/4885ALDH1A1 4664/4885
US-20030027063-A1 Apparatus and materials for three-dimensional optical data storage and retrieval RPL13, EIF2B3, MAP1LC3A SHBG 4775/4885DHFR 4796/4885ALDH1A1 4603/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.