Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.36 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.36 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | UBE2M | P61081 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28298086 | 0.87 | GPR35 (0.36) | ALDH1A1GAATAS1R3TAS1R1TAS1R2 | |
| SCHEMBL4449528 | 0.78 | — | — | |
| SCHEMBL5139533 | 0.75 | RAB9A (0.38) | ALDH1A1TAS1R3TAS1R1TAS1R2TDP1 | |
| Bromide SCHEMBL11733192 | 0.74 | SMN1; SMN2 (0.37) | ALDH1A1GAATAS1R3TAS1R1TAS1R2 | |
| Hydrochloric Acid SCHEMBL11734144 | 0.74 | TDP1 (0.41) | ALDH1A1GAATAS1R3TAS1R1TAS1R2 | |
| SCHEMBL28393356 | 0.73 | TDP1 (0.39) | ALDH1A1TAS1R3TAS1R1TAS1R2TDP1 | |
| SCHEMBL5073994 | 0.69 | LMNA (0.36) | ALDH1A1TAS1R3TAS1R1TAS1R2TDP1 | |
| SCHEMBL9935445 | 0.66 | S100A4 (0.41) | ALDH1A1TDP1RAB9AMAPTLMNA | |
| SCHEMBL5074722 | 0.65 | ALDH1A1 (0.40) | ALDH1A1TDP1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL11817643 | 0.64 | TDP1 (0.45) | ALDH1A1GAATDP1GPR35RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007109201-A2 | BICYCLOHETEROARYL COMPOUNDS AS P2X7 MODULATORS AND USES THEREOF | RENOVIS, INC. (US) | 2007-09-27 | — | — | WO | disclosed |