Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | PDPK1 | O15530 | 4/20 | 0.39 |
| ▸ | PARP1 | P09874 | 6/20 | 0.38 |
| ▸ | BCL2 | P10415 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | XDH | P47989 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | PNP | P00491 | 2/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | GDA | Q9Y2T3 | 1/20 | 0.34 |
| ▸ | AURKA | O14965 | 1/20 | 0.34 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.34 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hypoxanthine SCHEMBL30266940 | 0.71 | TSHR (0.45) | ALDH1A1PDPK1PARP1BCL2MCL1 | |
| SCHEMBL14094281 | 0.71 | SMN1; SMN2 (0.46) | ALDH1A1PDPK1PARP1BCL2MCL1 | |
| SCHEMBL30804836 | 0.71 | ALDH1A1 (0.35) | ALDH1A1PDPK1LMNATSHRADORA2A | |
| SCHEMBL2473003 | 0.68 | ALDH1A1 (0.64) | ALDH1A1PDPK1LMNATSHRADORA2A | |
| Hypoxanthine SCHEMBL31181347 | 0.67 | ACHE (0.38) | ALDH1A1PDPK1PARP1BCL2MCL1 | |
| Guanine SCHEMBL5259 | 0.64 | ALDH1A1 (0.61) | ALDH1A1PARP1LMNAXDHSMN1; SMN2 | |
| SCHEMBL8278860 | 0.64 | PARP1 (0.43) | ALDH1A1PDPK1PARP1PNPACHE | |
| SCHEMBL19690932 | 0.64 | PNP (0.41) | ALDH1A1PDPK1PARP1BCL2MCL1 | |
| SCHEMBL21896056 | 0.64 | PNP (0.41) | ALDH1A1PDPK1PARP1BCL2MCL1 | |
| SCHEMBL4650483 | 0.64 | PNP (0.41) | ALDH1A1PDPK1PARP1BCL2MCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8809328-B2 | Imidazole derivative | NATIONAL UNIVERSITY CORPORATION SHIZUOKA UNIVERSITY (JP) | 2014-08-19 | — | — | US | claimed |
| US-20140148598-A1 | IMIDAZOLE DERIVATIVE | NATIONAL UNIVERSITY CORPORATION SHIZUOKA UNIVERSITY (JP) | 2014-05-29 | — | — | US | claimed |
| EP-2703403-A1 | IMIDAZOLE DERIVATIVE | BASF SE (DE) | 2014-03-05 | — | — | EP | claimed |
| US-12527801-B2 | Cell activator of animal cell | VITAMIN C60 BIORESEARCH CORPORATION (JP) | 2026-01-20 | — | — | US | disclosed |
| EP-3960244-B1 | CELL ACTIVATOR OF ANIMAL CELL | VITAMIN C60 BIORESEARCH CORP (JP) | 2025-04-09 | — | — | EP | disclosed |
| US-20250017918-A1 | ORAL SUSPENSIONS COMPRISING TEMOZOLOMIDE OR LENALIDOMIDE | SHORLA PHARMA LTD (IE) | 2025-01-16 | — | — | US | disclosed |
| CN-112955116-B | Cell activator for animal cells | 维生素C60生化学研究公司 | 2023-10-27 | — | — | CN | disclosed |
| US-20220233547-A1 | CELL ACTIVATOR OF ANIMAL CELL | MITSUBISHI CORPORATION LIFE SCIENCES LIMITED (JP) | 2022-07-28 | — | — | US | disclosed |
| EP-3960244-A1 | CELL ACTIVATOR OF ANIMAL CELL | Vitamin C60 Bioresearch Corporation (JP) | 2022-03-02 | — | — | EP | disclosed |
| CN-112955116-A | Cell activator for animal cells | 维生素C60生化学研究公司 | 2021-06-11 | — | — | CN | disclosed |
| CN-112442036-A | Novel purinone and imidazotriazinone derivatives having anti-glioma activity | 南开大学 | 2021-03-05 | — | — | CN | disclosed |
| US-8232392-B2 | Process for preparing temozolomide | CHEMI S.P.A. (IT) | 2012-07-31 | — | — | US | disclosed |
| US-20120122690-A1 | Method For Increasing Yield Of Staple Food Crop | NATIONAL UNIVERSITY CORPORATION SHIZUOKA (JP) | 2012-05-17 | — | — | US | disclosed |
| US-20120122690-A1 | Method For Increasing Yield Of Staple Food Crop | NATIONAL UNIVERSITY CORPORATION SHIZUOKA (JP) | 2012-05-17 | — | — | US | disclosed |
| EP-2374807-A2 | An improved process for the isolation of temozolomide | CIPLA LIMITED (IN) | 2011-10-12 | — | — | EP | disclosed |
| US-20100036121-A1 | Process for preparing temozolomide | CHEMI S.P.A. (IT) | 2010-02-11 | — | — | US | disclosed |
| US-20100036121-A1 | Process for preparing temozolomide | CHEMI S.P.A. (IT) | 2010-02-11 | — | — | US | disclosed |
| US-20090326028-A1 | Process for the preparation of temozolomide and analogs | CIPLA LIMITED (IN) | 2009-12-31 | — | — | US | disclosed |
| US-20090326028-A1 | Process for the preparation of temozolomide and analogs | CIPLA LIMITED (IN) | 2009-12-31 | — | — | US | disclosed |
| WO-2008038031-A1 | AN IMPROVED PROCESS FOR THE PREPARATION OF TEMOZOLOMIDE AND ANALOGS | CIPLA LIMITED (IN) | 2008-04-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120122690-A1 | Method For Increasing Yield Of Staple Food Crop | SI, H1-0, H1-3 | ALDH1A1 4642/4885PDPK1 2241/4885PARP1 3223/4885 |
| US-20140148598-A1 | IMIDAZOLE DERIVATIVE | ING2, DCUN1D5, IGF1R | ALDH1A1 1509/4885PDPK1 608/4885PARP1 3604/4885 |
| US-20220233547-A1 | CELL ACTIVATOR OF ANIMAL CELL | IL2, IL15, NFATC1 | ALDH1A1 740/4885PDPK1 2783/4885PARP1 2122/4885 |
| US-20090326028-A1 | Process for the preparation of temozolomide and analogs | IDH3A, IDH3B, IDH2 | ALDH1A1 309/4885PDPK1 2709/4885PARP1 1663/4885 |
| US-12527801-B2 | Cell activator of animal cell | DSG1, DSC1, KRT18 | ALDH1A1 2037/4885PDPK1 844/4885PARP1 4313/4885 |
| US-20100036121-A1 | Process for preparing temozolomide | MGMT, NNMT, NOS2 | ALDH1A1 1519/4885PDPK1 4185/4885PARP1 441/4885 |
| US-20250017918-A1 | ORAL SUSPENSIONS COMPRISING TEMOZOLOMIDE OR LENALIDOMIDE | MALT1, SMN1; SMN2, MGMT | ALDH1A1 4194/4885PDPK1 1986/4885PARP1 3193/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.