Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.62 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.62 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 5/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | KAT2B | Q92831 | 2/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 3/20 | 0.45 |
| ▸ | MITF | O75030 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29580086 | 1.00 | TSHR (0.67) | TSHRCYP3A4ALDH1A1HIF1AVCAM1 | |
| SCHEMBL247992 | 0.83 | TSHR (0.67) | TSHRCYP3A4ALDH1A1HIF1AVCAM1 | |
| SCHEMBL29384695 | 0.83 | TSHR (0.67) | TSHRCYP3A4ALDH1A1HIF1AVCAM1 | |
| SCHEMBL2654598 | 0.81 | ALDH1A1 (0.50) | TSHRCYP3A4ALDH1A1HIF1AVCAM1 | |
| SCHEMBL294724 | 0.80 | TSHR (1.00) | TSHRCYP3A4ALDH1A1RECQLGPR35 | |
| SCHEMBL11189916 | 0.78 | TSHR (0.72) | TSHRCYP3A4ALDH1A1LMNARECQL | |
| SCHEMBL29462663 | 0.78 | ATM (0.69) | TSHRALDH1A1HIF1AVCAM1LMNA | |
| SCHEMBL102780 | 0.78 | ATM (0.69) | TSHRALDH1A1HIF1AVCAM1LMNA | |
| SCHEMBL11579276 | 0.78 | ALDH1A1 (0.67) | TSHRALDH1A1HIF1AVCAM1LMNA | |
| SCHEMBL29613904 | 0.78 | TSHR (0.72) | TSHRCYP3A4ALDH1A1LMNARECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 650 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117659017-B | TRPML1/2 modulator compound, pharmaceutical composition, preparation method and application thereof | 北京华益健康药物研究中心 | 2026-05-15 | — | — | CN | disclosed |
| EP-4724543-A1 | IRIDIUM COMPLEXES USED AS PHOTOSENSITIZERS | Université Grenoble Alpes (FR) | 2026-04-15 | — | — | EP | disclosed |
| EP-4652154-A1 | NOVEL ALPK1 INHIBITORS | Pyrotech (Beijing) Biotechnology Co., Ltd. (CN) | 2025-11-26 | — | — | EP | disclosed |
| US-12466815-B2 | Carboxamide compounds and uses thereof | INCYTE CORPORATION (US) | 2025-11-11 | — | — | US | disclosed |
| US-12421218-B2 | Substituted pyrazine-carboxamide derivatives | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2025-09-23 | — | — | US | disclosed |
| EP-4608822-A1 | NOVEL SUBSTITUTED PYRAZINE-CARBOXAMIDE DERIVATIVES | Boehringer Ingelheim International GmbH (DE) | 2025-09-03 | — | — | EP | disclosed |
| US-20250243168-A1 | ACETYL-COA SYNTHETASE 2 (ACSS2) INHIBITORS AND METHODS USING SAME | THE WISTAR INST (US) | 2025-07-31 | — | — | US | disclosed |
| US-12338226-B2 | Substituted benzodiazoles and use thereof in therapy | THOMAS HELLEDAYS STIFTELSE FOR MEDICINSK FORSKNING (SE) | 2025-06-24 | — | — | US | disclosed |
| CN-120091815-A | T-type voltage-gated calcium channel enhancer | 广泛研究所股份有限公司 | 2025-06-03 | — | — | CN | disclosed |
| CN-120077036-A | Novel substituted pioglitazone oxazine carboxamide derivatives | 勃林格殷格翰国际有限公司 | 2025-05-30 | — | — | CN | disclosed |
| EP-0129692-A2 | Dibenzodiazepin derivatives, a process for their preparation and their use as medicaments | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1985-01-02 | — | — | EP | disclosed |
| US-4224340-A | Anti-inflammatory compositions containing α-phenyl-N-phenylnitrone compounds | WILLIAM H. RORER, INC. (US) | 1980-09-23 | — | — | US | disclosed |
| US-4214003-A | ANTIINFLAMMATORY AGENTS | WILLIAM H. RORER, INC. (US) | 1980-07-22 | — | — | US | disclosed |
| US-4197314-A | WITH A DIPHENYL NITRONE | WILLIAM H. RORER, INC. (US) | 1980-04-08 | — | — | US | disclosed |
| US-4182872-A | CORRESPONDING 4-CARBOBENZOXY COMPOUNDS, 2,3,4,4A-TETRAHYDRO-1H-PYRAZINO(1,2-A)QUINOXALIN-5(6H)-ONES, 2,3,4,4A,5,6-HEXAHYDRO-1H-PYRAZINO(1,2-A)QUINOXALINES, HYPOTENSIVE | AMERICAN HOME PRODUCTS CORPORATION (US) | 1980-01-08 | — | — | US | disclosed |
| US-4182869-A | HYPOTENSIVE AGENTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1980-01-08 | — | — | US | disclosed |
| US-4153722-A | ANTIINFLAMMATORY, A-PHENYL-N-PHENYLNITRONE | WILLIAM H. RORER, INC. (US) | 1979-05-08 | — | — | US | disclosed |
| US-4138567-A | HYPOTENSIVE | AMERICAN HOME PRODUCTS CORPORATION (US) | 1979-02-06 | — | — | US | disclosed |
| US-4089958-A | HYPOTENSIVE AGENTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1978-05-16 | — | — | US | disclosed |
| US-4032639-A | 2,3,4,4A-Tetrahydro-1H-pyrazino[1,2-a,]quinoxalin-5(6H)-ones and derivatives thereof for relieving hypertension | AMERICAN HOME PRODUCTS CORPORATION (US) | 1977-06-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12421218-B2 | Substituted pyrazine-carboxamide derivatives | GRM4, GRIA4, GRM1 | TSHR 430/4885CYP3A4 309/4885ALDH1A1 1762/4885 |
| US-12466815-B2 | Carboxamide compounds and uses thereof | PCK1, PHKG2, PHKG1 | TSHR 4815/4885CYP3A4 1958/4885ALDH1A1 2561/4885 |
| US-20250243168-A1 | ACETYL-COA SYNTHETASE 2 (ACSS2) INHIBITORS AND METHODS USING SAME | ACSS2, ACACB, ACACA | TSHR 4791/4885CYP3A4 3058/4885ALDH1A1 170/4885 |
| US-12338226-B2 | Substituted benzodiazoles and use thereof in therapy | XDH, CYP11B2, CYP4X1 | TSHR 1665/4885CYP3A4 10/4885ALDH1A1 274/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.