Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 1/20 | 0.32 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.32 |
| ▸ | CDC25B | P30305 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | PTGES | O14684 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6130233 | 0.71 | TUBB4A (0.44) | LMNAMAPTMAPK1HSD17B10 | |
| Hydrochloric Acid SCHEMBL5565982 | 0.65 | ALDH1A1 (0.40) | KDRLMNAMAPT | |
| Hydrochloric Acid SCHEMBL6130242 | 0.64 | ARG1 (0.39) | MAPTMAPK1HSD17B10 | |
| Hydrochloric Acid SCHEMBL28596229 | 0.64 | LMNA (0.36) | LMNAMAPTMAPK1 | |
| Hydrochloric Acid SCHEMBL6130235 | 0.64 | ARG1 (0.41) | MAPTMAPK1HSD17B10 | |
| SCHEMBL6462907 | 0.62 | LMNA (0.38) | LMNA | |
| SCHEMBL15934313 | 0.61 | ALDH1A1 (0.41) | KDRMAPTHSD17B10 | |
| SCHEMBL3034620 | 0.61 | PLA2G7 (0.50) | — | |
| Hydrochloric Acid SCHEMBL5565999 | 0.60 | KDR (0.41) | KDR | |
| SCHEMBL24703392 | 0.60 | POLB (0.65) | MTNR1BLMNAMAPTMAPK1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7229479-B2 | Method of coloring porous material | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2007-06-12 | — | — | US | disclosed |
| US-20060162095-A1 | Method of colouring porous material | CIBA SPECIALTY CHEMICALS CORP. | 2006-07-27 | — | — | US | disclosed |
| EP-1534226-A1 | METHOD OF COLOURING POROUS MATERIAL | Ciba SC Holding AG (CH) | 2005-06-01 | — | — | EP | disclosed |
| WO-2004019897-A1 | METHOD OF COLOURING POROUS MATERIAL | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2004-03-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060162095-A1 | Method of colouring porous material | ACR, HLA-C, TYR | KDR 4077/4885MTNR1B 4231/4885CDC25B 1640/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.