Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VDR | P11473 | 3/20 | 0.85 |
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.68 |
| ▸ | HPGD | P15428 | 7/20 | 0.68 |
| ▸ | MAPT | P10636 | 9/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.67 |
| ▸ | MEN1 | O00255 | 6/20 | 0.66 |
| ▸ | PARL | Q9H300 | 2/20 | 0.64 |
| ▸ | F2 | P00734 | 4/20 | 0.63 |
| ▸ | HTT | P42858 | 3/20 | 0.58 |
| ▸ | XBP1 | P17861 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29370293 | 0.92 | VDR (1.00) | VDRKDM4EALDH1A1HPGDMAPT | |
| SCHEMBL64277 | 0.92 | VDR (1.00) | VDRKDM4EALDH1A1HPGDMAPT | |
| SCHEMBL64214 | 0.89 | PARL (0.68) | VDRKDM4EALDH1A1HPGDMAPT | |
| SCHEMBL22251878 | 0.83 | VDR (0.61) | VDRKDM4EALDH1A1HPGDMAPT | |
| SCHEMBL462047 | 0.81 | ALDH1A1 (1.00) | VDRKDM4EALDH1A1HPGDMAPT | |
| SCHEMBL64368 | 0.81 | KDM4E (1.00) | VDRKDM4EALDH1A1HPGDMAPT | |
| SCHEMBL12339094 | 0.80 | PARL (0.81) | VDRKDM4EALDH1A1HPGDMAPT | |
| SCHEMBL5556208 | 0.80 | VDR (0.77) | VDRKDM4EALDH1A1HPGDMAPT | |
| SCHEMBL14099607 | 0.80 | VDR (0.76) | VDRKDM4EALDH1A1HPGDMAPT | |
| SCHEMBL2468373 | 0.80 | KMT2A (1.00) | VDRKDM4EALDH1A1HPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7244544-B2 | Oxime derivatives and the use thereof as latent acids | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2007-07-17 | — | — | US | disclosed |