SCHEMBL5583841

SCHEMBL5583841

COc1ccnc(C(=O)Nc2c(C)cc(Oc3ccccc3)cc2C)c1O

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.43
PDGFRA P16234 5/20 0.41
KIT P10721 3/20 0.41
KDR P35968 2/20 0.41
ALDH1A1 P00352 2/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
GCK P35557 1/20 0.40
AXL P30530 1/20 0.39
RAB9A P51151 2/20 0.39
NPC1 O15118 1/20 0.39
PKM P14618 1/20 0.39
MEN1 O00255 3/20 0.39
KMT2A Q03164 3/20 0.39
GRM4 Q14833 1/20 0.39
EGLN1 Q9GZT9 1/20 0.39
CASP3 P42574 1/20 0.38
SENP8 Q96LD8 1/20 0.38
SENP7 Q9BQF6 1/20 0.38
SENP6 Q9GZR1 1/20 0.38
KDM4E B2RXH2 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2237038 0.84 RAB9A (0.53) MAPTPDGFRAKITKDRALDH1A1
SCHEMBL5583770 0.83 GRM4 (0.52) MAPTPDGFRAKDRRAB9ANPC1
SCHEMBL5583760 0.83 STK39 (0.56) PDGFRAKITKDRAXLRAB9A
SCHEMBL21186013 0.82 RIPK1 (0.44) MAPTALDH1A1L3MBTL1RAB9ANPC1
SCHEMBL5583728 0.82 KMT2A (0.56) MAPTKDRALDH1A1RAB9ANPC1
SCHEMBL5583560 0.81 PKM (0.42) MAPTRAB9APKM
SCHEMBL5583631 0.81 RAB9A (0.58) MAPTPDGFRAKDRALDH1A1L3MBTL1
SCHEMBL5584055 0.79 ABCC1 (0.53) MAPTPDGFRAKITKDRAXL
SCHEMBL14284574 0.78 GRM4 (0.49) MAPTPDGFRAKDRRAB9ANPC1
SCHEMBL14159871 0.78 MAPK1 (0.54) PDGFRAKITKDRALDH1A1AXL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7183278-B1 Picolinamide derivative and harmful organism control agent comprising said picolinamide derivative as active component MEIJI SEIKA KAISHA, LTD. (JP) 2007-02-27 US disclosed
EP-1134214-A1 PICOLINAMIDE DERIVATIVES AND PEST CONTROLLERS CONTAINING THE SAME AS THE ACTIVE INGREDIENT MEIJI SEIKA KAISHA LTD. (JP) 2001-09-19 EP disclosed