Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK1 | P06493 | 1/20 | 0.43 |
| ▸ | KDR | P35968 | 1/20 | 0.43 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.41 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.41 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.41 |
| ▸ | CASP6 | P55212 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | MGLL | Q99685 | 1/20 | 0.39 |
| ▸ | ILK | Q13418 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5103181 | 0.91 | ALDH1A1 (0.43) | CDK1KDRMAPK10MAPK8MAPK9 | |
| SCHEMBL5096401 | 0.91 | ILK (0.48) | CDK1KDRMAPK10MAPK8MAPK9 | |
| SCHEMBL5100115 | 0.90 | PTGS1 (0.41) | CDK1KDRMAPK10MAPK8MAPK9 | |
| SCHEMBL5103578 | 0.88 | SMN1; SMN2 (0.46) | CDK1KDRNPC1RAB9ALMNA | |
| SCHEMBL5110395 | 0.86 | ALDH1A1 (0.46) | CDK1KDRMAPK10MAPK8MAPK9 | |
| SCHEMBL17709604 | 0.86 | MAPK10 (0.56) | CDK1KDRMAPK10MAPK8MAPK9 | |
| SCHEMBL5138885 | 0.84 | CSNK1D (0.41) | CDK1KDRMAPK10MAPK8MAPK9 | |
| SCHEMBL5596497 | 0.84 | KDM4E (0.42) | CDK1KDRMAPK10MAPK9NPC1 | |
| SCHEMBL5596747 | 0.81 | CDK1 (0.35) | CDK1KDRMAPK10MAPK8MAPK9 | |
| SCHEMBL5103679 | 0.76 | IRAK4 (0.46) | KDRMGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1696909-B1 | BENZOTHIAZOLE DERIVATIVES FOR THE TREATMENT OF DIABETES | SERONO LAB (CH) | 2007-11-14 | — | — | EP | claimed |