Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | JMJD7 | P0C870 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | STAT3 | P40763 | 1/20 | 0.40 |
| ▸ | STAT1 | P42224 | 1/20 | 0.40 |
| ▸ | AGPAT2 | O15120 | 1/20 | 0.40 |
| ▸ | ILK | Q13418 | 3/20 | 0.39 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5103181 | 0.86 | ALDH1A1 (0.43) | KDM4EMAPTNPC1GAARAB9A | |
| SCHEMBL5596244 | 0.84 | CDK1 (0.43) | KDM4EMAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL5096401 | 0.84 | ILK (0.48) | KDM4EMAPTNPC1GAARAB9A | |
| SCHEMBL5103578 | 0.84 | SMN1; SMN2 (0.46) | KDM4EMAPTNPC1GAARAB9A | |
| SCHEMBL17709604 | 0.83 | MAPK10 (0.56) | KDM4ENPC1RAB9AALDH1A1HPGD | |
| SCHEMBL5103679 | 0.83 | IRAK4 (0.46) | POLBIRAK4KDR | |
| SCHEMBL5110395 | 0.82 | ALDH1A1 (0.46) | KDM4EMAPTNPC1GAARAB9A | |
| SCHEMBL5138885 | 0.82 | CSNK1D (0.41) | KDM4EMAPTNPC1GAARAB9A | |
| SCHEMBL5100115 | 0.82 | PTGS1 (0.41) | MAPTNPC1RAB9AAGPAT2ILK | |
| SCHEMBL5596747 | 0.80 | CDK1 (0.35) | MAPTNPC1RAB9ASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1696909-B1 | BENZOTHIAZOLE DERIVATIVES FOR THE TREATMENT OF DIABETES | SERONO LAB (CH) | 2007-11-14 | — | — | EP | claimed |