Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 2/20 | 0.37 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.32 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.32 |
| ▸ | ITGAV | P06756 | 1/20 | 0.32 |
| ▸ | RXRA | P19793 | 1/20 | 0.32 |
| ▸ | RXRB | P28702 | 1/20 | 0.32 |
| ▸ | RXRG | P48443 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | XPO1 | O14980 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.30 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.30 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20184827 | 0.86 | RXRA (0.33) | CES2RXRARXRBRXRG | |
| SCHEMBL20184786 | 0.77 | TSHR (0.48) | CES2IDO1MAPTTSHRALDH1A1 | |
| SCHEMBL440959 | 0.76 | CES2 (0.58) | CES2IDO1ADRB1MAPTRAPGEF4 | |
| SCHEMBL5459115 | 0.76 | CES2 (0.42) | CES2IDO1ADRB1MAPTRAPGEF4 | |
| SCHEMBL432591 | 0.74 | CES2 (0.41) | CES2IDO1ADRB1MAPTRAPGEF4 | |
| SCHEMBL14763886 | 0.74 | GABRA1 (0.46) | MAPTRXRARXRBRXRGTSHR | |
| SCHEMBL81205 | 0.69 | CES2 (0.46) | CES2IDO1ADRB1MAPTRAPGEF4 | |
| SCHEMBL9482063 | 0.67 | RXRA (0.54) | CES2IDO1ADRB1MAPTRAPGEF4 | |
| SCHEMBL13567133 | 0.67 | CES2 (0.50) | CES2IDO1ADRB1MAPTRAPGEF4 | |
| SCHEMBL13866628 | 0.65 | RXRA (0.52) | CES2IDO1ADRB1MAPTRAPGEF4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140235867-A1 | METHOD FOR PRODUCING ALPHA-HYDROXY KETONE COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2014-08-21 | — | — | US | disclosed |
| EP-1312605-B1 | Method for producing biaryl compounds | SUMITOMO CHEMICAL CO (JP) | 2007-04-25 | — | — | EP | disclosed |
| EP-1312605-A1 | Method for producing biaryl compounds | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2003-05-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140235867-A1 | METHOD FOR PRODUCING ALPHA-HYDROXY KETONE COMPOUND | HSD17B7, BCKDK, HSD11B1 | CES2 690/4885IDO1 3687/4885ADRB1 524/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.