SCHEMBL562129

SCHEMBL562129

NC(=O)OCC1CCCC1

nearest known ligand 0.52

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.52
PARP10 Q53GL7 6/20 0.46
PARP15 Q460N3 5/20 0.46
SLC1A3 P43003 4/20 0.44
SLC1A2 P43004 4/20 0.44
SLC1A1 P43005 4/20 0.44
ALOX5 P09917 3/20 0.43
PARP2 Q9UGN5 2/20 0.42
ALOX15 P16050 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL562319 0.98 LMNA (0.55) LMNAPARP10PARP15SLC1A3SLC1A2
SCHEMBL8396762 0.98 LMNA (0.55) LMNAPARP10PARP15SLC1A3SLC1A2
SCHEMBL561524 0.95
SCHEMBL30427433 0.90 PARP15 (0.42) LMNAPARP10PARP15SLC1A3SLC1A2
SCHEMBL111361 0.90
Acetic Acid SCHEMBL4306790 0.90 LMNA (0.53) LMNAPARP10PARP15SLC1A3SLC1A2
Hydrochloric Acid SCHEMBL28974199 0.88
SCHEMBL21029278 0.82 LMNA (0.39) LMNAPARP10PARP15SLC1A3SLC1A2
SCHEMBL5861626 0.82 LMNA (0.48) LMNAPARP10PARP15SLC1A3SLC1A2
SCHEMBL2633967 0.82 PARP15 (0.38) LMNAPARP10PARP15SLC1A3SLC1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 64 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3619204-B1 COMPOUNDS FOR THE TREATMENT OF RESPIRATORY DISEASES TIANLI BIOTECH PTY LTD (AU) 2025-10-01 EP disclosed
US-20220380343-A1 COMPOUNDS FOR THE TREATMENT OF RESPIRATORY DISEASES TIANLI BIOTECH PTY LTD (AU) 2022-12-01 US disclosed
US-10596154-B2 3-(1H-imidazo[4,5-C]pyridin-2-yl)-1H-pyrazolo[3,4-C]pyridine and therapeutic uses thereof SAMUMED, LLC (US) 2020-03-24 US disclosed
US-20200079757-A1 COMPOUNDS FOR THE TREATMENT OF RESPIRATORY DISEASES THE UNIVERSITY OF MELBOURNE (AU) 2020-03-12 US disclosed
EP-3619204-A1 COMPOUNDS FOR THE TREATMENT OF RESPIRATORY DISEASES The University of Melbourne (AU) 2020-03-11 EP disclosed
CN-110753688-A Compounds for the treatment of respiratory diseases 墨尔本大学 2020-02-04 CN disclosed
US-20190119303-A1 3-(3H-IMIDAZO[4,5-B]PYRIDIN-2-YL)-1H-PYRAZOLO[3,4-B]PYRIDINE AND THERAPEUTIC USES THEREOF VICKERS VENTURE FUND VI PTE. LTD. (SG) 2019-04-25 US disclosed
US-10131677-B2 3-(3H-imidazo[4,5-B]pyridin-2-yl)-1H-pyrazolo[3,4-B]pyridine and therapeutic uses thereof SAMUMED, LLC (US) 2018-11-20 US disclosed
US-20180325910-A1 3-(1H-IMIDAZO[4,5-C]PYRIDIN-2-YL)-1H-PYRAZOLO[3,4-B]PYRIDINE AND THERAPEUTIC USES THEREOF VICKERS-SPLICE CO-INVESTMENT LLC (KY) 2018-11-15 US disclosed
WO-2018201192-A1 COMPOUNDS FOR THE TREATMENT OF RESPIRATORY DISEASES THE UNIVERSITY OF MELBOURNE (AU) 2018-11-08 WO disclosed
WO-2007005838-A2 HCV INHIBITORS VIROBAY, INC. (US) 2007-01-11 WO disclosed
EP-1673385-A4 MACROCYCLIC PEPTIDES ACTIVE AGAINST THE HEPATITIS C VIRUS BOEHRINGER INGELHEIM INT (DE) 2006-10-04 EP disclosed
EP-1673385-A1 MACROCYCLIC PEPTIDES ACTIVE AGAINST THE HEPATITIS C VIRUS Boehringer Ingelheim International GmbH (DE) 2006-06-28 EP disclosed
EP-1654261-A1 HEPATITIS C INHIBITOR COMPOUNDS Boehringer Ingelheim International GmbH (DE) 2006-05-10 EP disclosed
US-20050080005-A1 Macrocyclic peptides active against the hepatitis C virus BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2005-04-14 US disclosed
WO-2005028501-A1 MACROCYCLIC PEPTIDES ACTIVE AGAINST THE HEPATITIS C VIRUS BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2005-03-31 WO disclosed
US-20050020503-A1 Hepatitis C inhibitor compounds BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2005-01-27 US disclosed
WO-2004103996-A1 HEPATITIS C INHIBITOR COMPOUNDS BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2004-12-02 WO disclosed
US-5864043-A CARDIOVASCULAR DISORDERS AND ANGIOTENSIN ANTAGONIST KARL THOMAE GMBH (DE) 1999-01-26 US disclosed
US-5541229-A ANGIOITENSIN II ANTAGONIST AS HYPOTENSIVE AGENTS, ANTIISCHEMIC AGENTS AND CARDIOVASCULAR DISORDERS DR. KARL THOMAE GMBH (DE) 1996-07-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190119303-A1 3-(3H-IMIDAZO[4,5-B]PYRIDIN-2-YL)-1H-PYRAZOLO[3,4-B]PYRIDINE AND THERAPEUTIC USES THEREOF WNT1, WNT3, WNT3A LMNA 2964/4885PARP10 1302/4885PARP15 387/4885
US-10596154-B2 3-(1H-imidazo[4,5-C]pyridin-2-yl)-1H-pyrazolo[3,4-C]pyridine and therapeutic uses thereof WNT1, WNT3, WNT3A LMNA 2378/4885PARP10 1523/4885PARP15 494/4885
US-10131677-B2 3-(3H-imidazo[4,5-B]pyridin-2-yl)-1H-pyrazolo[3,4-B]pyridine and therapeutic uses thereof WNT1, WNT3, WNT3A LMNA 2964/4885PARP10 1302/4885PARP15 387/4885
US-20220380343-A1 COMPOUNDS FOR THE TREATMENT OF RESPIRATORY DISEASES LTC4S, LTB4R2, LTB4R LMNA 1444/4885PARP10 2679/4885PARP15 2509/4885
US-20050020503-A1 Hepatitis C inhibitor compounds HAVCR2, CTRL, CTRC LMNA 816/4885PARP10 1314/4885PARP15 3473/4885
US-20200079757-A1 COMPOUNDS FOR THE TREATMENT OF RESPIRATORY DISEASES LTC4S, LTB4R2, LTB4R LMNA 1444/4885PARP10 2679/4885PARP15 2509/4885
US-20180325910-A1 3-(1H-IMIDAZO[4,5-C]PYRIDIN-2-YL)-1H-PYRAZOLO[3,4-B]PYRIDINE AND THERAPEUTIC USES THEREOF WNT1, WNT3, WNT3A LMNA 2571/4885PARP10 1520/4885PARP15 465/4885
US-20050080005-A1 Macrocyclic peptides active against the hepatitis C virus CTRL, RPP30, RNASE1 LMNA 2550/4885PARP10 1858/4885PARP15 4211/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.